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Phase I, double-blind, randomized, placebo-controlled, dose-escalation study of NI-0401 (a fully human anti-CD3 monoclonal antibody) in patients with moderate to severe active Crohn's disease.
van der Woude CJ, Stokkers P, van Bodegraven AA, Van Assche G, Hebzda Z, Paradowski L, D'Haens G, Ghosh S, Feagan B, Rutgeerts P, Dijkstra G, de Jong DJ, Oldenburg B, Farhan M, Richard T, Dean Y, Hommes DW; Initiative on Crohn's and Colitis, The Netherlands. van der Woude CJ, et al. Among authors: dijkstra g. Inflamm Bowel Dis. 2010 Oct;16(10):1708-16. doi: 10.1002/ibd.21252. Inflamm Bowel Dis. 2010. PMID: 20848453 Clinical Trial.
Histomorphometric analysis reveals reduced bone mass and bone formation in patients with quiescent Crohn's disease.
Oostlander AE, Bravenboer N, Sohl E, Holzmann PJ, van der Woude CJ, Dijkstra G, Stokkers PC, Oldenburg B, Netelenbos JC, Hommes DW, van Bodegraven AA, Lips P; Dutch Initiative on Crohn and Colitis (ICC). Oostlander AE, et al. Among authors: dijkstra g. Gastroenterology. 2011 Jan;140(1):116-23. doi: 10.1053/j.gastro.2010.09.007. Epub 2010 Sep 18. Gastroenterology. 2011. PMID: 20854819
Malignant transformation of perianal and enterocutaneous fistulas is rare: results of 17 years of follow-up from The Netherlands.
Baars JE, Kuipers EJ, Dijkstra G, Hommes DW, de Jong DJ, Stokkers PC, Oldenburg B, Pierik M, Wahab PJ, van Bodegraven AA, van der Woude CJ; Initiative for Crohn and Colitis. Baars JE, et al. Among authors: dijkstra g. Scand J Gastroenterol. 2011 Mar;46(3):319-25. doi: 10.3109/00365521.2010.536251. Scand J Gastroenterol. 2011. PMID: 21299339
Farnesoid X receptor (FXR) activation and FXR genetic variation in inflammatory bowel disease.
Nijmeijer RM, Gadaleta RM, van Mil SW, van Bodegraven AA, Crusius JB, Dijkstra G, Hommes DW, de Jong DJ, Stokkers PC, Verspaget HW, Weersma RK, van der Woude CJ, Stapelbroek JM, Schipper ME, Wijmenga C, van Erpecum KJ, Oldenburg B; Dutch Initiative on Crohn, Colitis (ICC). Nijmeijer RM, et al. Among authors: dijkstra g. PLoS One. 2011;6(8):e23745. doi: 10.1371/journal.pone.0023745. Epub 2011 Aug 22. PLoS One. 2011. PMID: 21887309 Free PMC article.
371 results