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Influenza, but not SARS-CoV-2, infection induces a rapid interferon response that wanes with age and diminished tissue-resident memory CD8+ T cells.
Nguyen TH, McAuley JL, Kim Y, Zheng MZ, Gherardin NA, Godfrey DI, Purcell DF, Sullivan LC, Westall GP, Reading PC, Kedzierska K, Wakim LM. Nguyen TH, et al. Among authors: reading pc. Clin Transl Immunology. 2021 Jan 26;10(1):e1242. doi: 10.1002/cti2.1242. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33532071 Free PMC article.
Oseltamivir Prophylaxis Reduces Inflammation and Facilitates Establishment of Cross-Strain Protective T Cell Memory to Influenza Viruses.
Bird NL, Olson MR, Hurt AC, Oshansky CM, Oh DY, Reading PC, Chua BY, Sun Y, Tang L, Handel A, Jackson DC, Turner SJ, Thomas PG, Kedzierska K. Bird NL, et al. Among authors: reading pc. PLoS One. 2015 Jun 18;10(6):e0129768. doi: 10.1371/journal.pone.0129768. eCollection 2015. PLoS One. 2015. PMID: 26086392 Free PMC article.
Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude.
Quinn KM, Kan WT, Watson KA, Liddicoat BJ, Swan NG, McQuilten H, Denton AE, Li J, Chen W, Brown LE, Jackson DC, Reading PC, Doherty PC, Kedzierska K, Kedzierski L, Turner SJ, La Gruta NL. Quinn KM, et al. Among authors: reading pc. PLoS One. 2017 Sep 8;12(9):e0184732. doi: 10.1371/journal.pone.0184732. eCollection 2017. PLoS One. 2017. PMID: 28886201 Free PMC article.
142 results