Spino C - Search Results

1

Constraining the Side Chain of C-Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile.

Trân K, Van Den Hauwe R, Sainsily X, Couvineau P, Côté J, Simard L, Echevarria M, Murza A, Serre A, Théroux L, Saibi S, Haroune L, Longpré JM, Lesur O, Auger-Messier M, Spino C, Bouvier M, Sarret P, Ballet S, Marsault É. Trân K, et al. Among authors: spino c. J Med Chem. 2021 May 13;64(9):5345-5364. doi: 10.1021/acs.jmedchem.0c01941. Epub 2021 Feb 1. J Med Chem. 2021. PMID: 33524256

2

Anti-HIV coumarins from Calophyllum seed oil.

Spino C, Dodier M, Sotheeswaran S. Spino C, et al. Bioorg Med Chem Lett. 1998 Dec 15;8(24):3475-8. doi: 10.1016/s0960-894x(98)00628-3. Bioorg Med Chem Lett. 1998. PMID: 9934455

3

Sterically biased 3,3-sigmatropic rearrangement of chiral allylic azides: application to the total syntheses of alkaloids.

Lauzon S, Tremblay F, Gagnon D, Godbout C, Chabot C, Mercier-Shanks C, Perreault S, DeSève H, Spino C. Lauzon S, et al. Among authors: spino c. J Org Chem. 2008 Aug 15;73(16):6239-50. doi: 10.1021/jo800817p. Epub 2008 Jul 22. J Org Chem. 2008. PMID: 18642871

4

Stereoselective synthesis of (+)-euphococcinine and (-)-adaline.

Arbour M, Roy S, Godbout C, Spino C. Arbour M, et al. Among authors: spino c. J Org Chem. 2009 May 15;74(10):3806-14. doi: 10.1021/jo9001992. J Org Chem. 2009. PMID: 19371091

5

Photochemical and thermal ring-contraction of cyclic hydroxamic acid derivatives.

Pichette S, Aubert-Nicol S, Lessard J, Spino C. Pichette S, et al. Among authors: spino c. J Org Chem. 2012 Dec 21;77(24):11216-26. doi: 10.1021/jo3023507. Epub 2012 Dec 13. J Org Chem. 2012. PMID: 23198744

6

Converting cycloalkanones into N-heterocycles: formal synthesis of (-)-gephyrotoxin 287C.

Pichette S, Winter DK, Lessard J, Spino C. Pichette S, et al. Among authors: spino c. J Org Chem. 2013 Dec 20;78(24):12532-44. doi: 10.1021/jo402217e. Epub 2013 Nov 13. J Org Chem. 2013. PMID: 24188015

7

O-Heterocycles from Unsaturated Carbonyls and Dimethoxycarbene.

Croisetière JP, Spino C. Croisetière JP, et al. Among authors: spino c. J Org Chem. 2018 May 18;83(10):5609-5618. doi: 10.1021/acs.joc.8b00613. Epub 2018 Apr 30. J Org Chem. 2018. PMID: 29682963

8

Stereocontrolled formation of amino acids and N-heterocycles bearing a quaternary chiral carbon.

Roy S, Spino C. Roy S, et al. Among authors: spino c. Org Lett. 2006 Mar 2;8(5):939-42. doi: 10.1021/ol053061g. Org Lett. 2006. PMID: 16494479

9

Mechanism and regioselectivity of the cycloaddition of thiones derived from Meldrum's acid, malonates, or other dicarbonyls.

Perreault S, Poirier M, Léveillé P, René O, Joly P, Dory Y, Spino C. Perreault S, et al. Among authors: spino c. J Org Chem. 2008 Oct 3;73(19):7457-66. doi: 10.1021/jo800945y. Epub 2008 Sep 5. J Org Chem. 2008. PMID: 18771325

10

Stereoselective synthesis of (+)-aspidofractinine.

Gagnon D, Spino C. Gagnon D, et al. Among authors: spino c. J Org Chem. 2009 Aug 21;74(16):6035-41. doi: 10.1021/jo9009497. J Org Chem. 2009. PMID: 19603751

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