Kasinath V - Search Results

1

JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications.

Kasinath V, Beck C, Sauer P, Poepsel S, Kosmatka J, Faini M, Toso D, Aebersold R, Nogales E. Kasinath V, et al. Science. 2021 Jan 22;371(6527):eabc3393. doi: 10.1126/science.abc3393. Science. 2021. PMID: 33479123 Free PMC article.

2

Structures of human PRC2 with its cofactors AEBP2 and JARID2.

Kasinath V, Faini M, Poepsel S, Reif D, Feng XA, Stjepanovic G, Aebersold R, Nogales E. Kasinath V, et al. Science. 2018 Feb 23;359(6378):940-944. doi: 10.1126/science.aar5700. Epub 2018 Jan 18. Science. 2018. PMID: 29348366 Free PMC article.

3

Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes.

Poepsel S, Kasinath V, Nogales E. Poepsel S, et al. Among authors: kasinath v. Nat Struct Mol Biol. 2018 Feb;25(2):154-162. doi: 10.1038/s41594-018-0023-y. Epub 2018 Jan 29. Nat Struct Mol Biol. 2018. PMID: 29379173 Free PMC article.

4

Recent Structural Insights into Polycomb Repressive Complex 2 Regulation and Substrate Binding.

Kasinath V, Poepsel S, Nogales E. Kasinath V, et al. Biochemistry. 2019 Feb 5;58(5):346-354. doi: 10.1021/acs.biochem.8b01064. Epub 2018 Dec 3. Biochemistry. 2019. PMID: 30451485 Free PMC article.

5

Structural basis for inactivation of PRC2 by G-quadruplex RNA.

Song J, Gooding AR, Hemphill WO, Love BD, Robertson A, Yao L, Zon LI, North TE, Kasinath V, Cech TR. Song J, et al. Among authors: kasinath v. Science. 2023 Sep 22;381(6664):1331-1337. doi: 10.1126/science.adh0059. Epub 2023 Sep 21. Science. 2023. PMID: 37733873

6

Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications.

Cookis T, Lydecker A, Sauer P, Kasinath V, Nogales E. Cookis T, et al. Among authors: kasinath v. bioRxiv [Preprint]. 2024 Feb 10:2024.02.09.579730. doi: 10.1101/2024.02.09.579730. bioRxiv. 2024. PMID: 38370759 Free PMC article. Preprint.

7

DNMT1 inhibition by pUG-fold quadruplex RNA.

Jansson-Fritzberg LI, Sousa CI, Smallegan MJ, Song JJ, Gooding AR, Kasinath V, Rinn JL, Cech TR. Jansson-Fritzberg LI, et al. Among authors: kasinath v. RNA. 2023 Mar;29(3):346-360. doi: 10.1261/rna.079479.122. Epub 2022 Dec 27. RNA. 2023. PMID: 36574982 Free PMC article.

8

Structural insights into the interactions of Polycomb Repressive Complex 2 with chromatin.

Iragavarapu AG, Yao L, Kasinath V. Iragavarapu AG, et al. Among authors: kasinath v. Biochem Soc Trans. 2021 Dec 17;49(6):2639-2653. doi: 10.1042/BST20210450. Biochem Soc Trans. 2021. PMID: 34747969 Free PMC article. Review.

9

Microscopic insights into the NMR relaxation-based protein conformational entropy meter.

Kasinath V, Sharp KA, Wand AJ. Kasinath V, et al. J Am Chem Soc. 2013 Oct 9;135(40):15092-100. doi: 10.1021/ja405200u. Epub 2013 Sep 25. J Am Chem Soc. 2013. PMID: 24007504 Free PMC article.

10

Dynamic and thermodynamic response of the Ras protein Cdc42Hs upon association with the effector domain of PAK3.

Moorman VR, Valentine KG, Bédard S, Kasinath V, Dogan J, Love FM, Wand AJ. Moorman VR, et al. Among authors: kasinath v. J Mol Biol. 2014 Oct 23;426(21):3520-38. doi: 10.1016/j.jmb.2014.07.031. Epub 2014 Aug 7. J Mol Biol. 2014. PMID: 25109462 Free PMC article.

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