Hotblack A - Search Results

1

Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma.

Agliardi G, Liuzzi AR, Hotblack A, De Feo D, Núñez N, Stowe CL, Friebel E, Nannini F, Rindlisbacher L, Roberts TA, Ramasawmy R, Williams IP, Siow BM, Lythgoe MF, Kalber TL, Quezada SA, Pule MA, Tugues S, Straathof K, Becher B. Agliardi G, et al. Among authors: hotblack a. Nat Commun. 2021 Jan 19;12(1):444. doi: 10.1038/s41467-020-20599-x. Nat Commun. 2021. PMID: 33469002 Free PMC article.

2

Near-infrared dual bioluminescence imaging in mouse models of cancer using infraluciferin.

Stowe CL, Burley TA, Allan H, Vinci M, Kramer-Marek G, Ciobota DM, Parkinson GN, Southworth TL, Agliardi G, Hotblack A, Lythgoe MF, Branchini BR, Kalber TL, Anderson JC, Pule MA. Stowe CL, et al. Among authors: hotblack a. Elife. 2019 Oct 15;8:e45801. doi: 10.7554/eLife.45801. Elife. 2019. PMID: 31610848 Free PMC article.

3

Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4⁺ T Cells.

Śledzińska A, Vila de Mucha M, Bergerhoff K, Hotblack A, Demane DF, Ghorani E, Akarca AU, Marzolini MAV, Solomon I, Vargas FA, Pule M, Ono M, Seddon B, Kassiotis G, Ariyan CE, Korn T, Marafioti T, Lord GM, Stauss H, Jenner RG, Peggs KS, Quezada SA. Śledzińska A, et al. Among authors: hotblack a. Immunity. 2020 Jan 14;52(1):151-166.e6. doi: 10.1016/j.immuni.2019.12.007. Epub 2020 Jan 7. Immunity. 2020. PMID: 31924474 Free PMC article.

4

Tunable control of CAR T cell activity through tetracycline mediated disruption of protein-protein interaction.

Hotblack A, Kokalaki EK, Palton MJ, Cheung GW, Williams IP, Manzoor S, Grothier TI, Piapi A, Fiaccadori V, Wawrzyniecka P, Roddy HA, Agliardi G, Roddie C, Onuoha S, Thomas S, Cordoba S, Pule M. Hotblack A, et al. Sci Rep. 2021 Nov 9;11(1):21902. doi: 10.1038/s41598-021-01418-9. Sci Rep. 2021. PMID: 34754016 Free PMC article.

5

Fine-tuning CARs for best performance.

Hotblack A, Straathof K. Hotblack A, et al. Cancer Cell. 2022 Jan 10;40(1):11-13. doi: 10.1016/j.ccell.2021.12.010. Cancer Cell. 2022. PMID: 35016025 Free article.

6

AKT inhibition generates potent polyfunctional clinical grade AUTO1 CAR T-cells, enhancing function and survival.

Mehra V, Agliardi G, Dias Alves Pinto J, Shafat MS, Garai AC, Green L, Hotblack A, Arce Vargas F, Peggs KS, van der Waart AB, Dolstra H, Pule MA, Roddie C. Mehra V, et al. Among authors: hotblack a. J Immunother Cancer. 2023 Sep;11(9):e007002. doi: 10.1136/jitc-2023-007002. J Immunother Cancer. 2023. PMID: 37709295 Free PMC article.

7

Tumor-Resident Dendritic Cells and Macrophages Modulate the Accumulation of TCR-Engineered T Cells in Melanoma.

Hotblack A, Holler A, Piapi A, Ward S, Stauss HJ, Bennett CL. Hotblack A, et al. Mol Ther. 2018 Jun 6;26(6):1471-1481. doi: 10.1016/j.ymthe.2018.03.011. Epub 2018 Mar 16. Mol Ther. 2018. PMID: 29628306 Free PMC article.

8

Expression of a dominant T-cell receptor can reduce toxicity and enhance tumor protection of allogeneic T-cell therapy.

Holler A, Zech M, Ghorashian S, Pike R, Hotblack A, Veliça P, Xue SA, Chakraverty R, Morris EC, Stauss HJ. Holler A, et al. Among authors: hotblack a. Haematologica. 2016 Apr;101(4):482-90. doi: 10.3324/haematol.2015.132712. Epub 2016 Jan 22. Haematologica. 2016. PMID: 26802053 Free PMC article.

9

Dendritic Cells Cross-Present Immunogenic Lentivector-Encoded Antigen from Transduced Cells to Prime Functional T Cell Immunity.

Hotblack A, Seshadri S, Zhang L, Hamrang-Yousefi S, Chakraverty R, Escors D, Bennett CL. Hotblack A, et al. Mol Ther. 2017 Feb 1;25(2):504-511. doi: 10.1016/j.ymthe.2016.11.001. Mol Ther. 2017. PMID: 28153097 Free PMC article.

10

4-1BB ligand activates bystander dendritic cells to enhance immunization in trans.

Macdonald DC, Hotblack A, Akbar S, Britton G, Collins MK, Rosenberg WC. Macdonald DC, et al. Among authors: hotblack a. J Immunol. 2014 Nov 15;193(10):5056-64. doi: 10.4049/jimmunol.1301723. Epub 2014 Oct 10. J Immunol. 2014. PMID: 25305314 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

11 results

Search Page