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Maturation of neuronal AD-tau pathology involves site-specific phosphorylation of cytoplasmic and synaptic tau preceding conformational change and fibril formation.
Aragão Gomes L, Uytterhoeven V, Lopez-Sanmartin D, Tomé SO, Tousseyn T, Vandenberghe R, Vandenbulcke M, von Arnim CAF, Verstreken P, Thal DR. Aragão Gomes L, et al. Among authors: verstreken p. Acta Neuropathol. 2021 Feb;141(2):173-192. doi: 10.1007/s00401-020-02251-6. Epub 2021 Jan 11. Acta Neuropathol. 2021. PMID: 33427938
Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation.
Calafate S, Buist A, Miskiewicz K, Vijayan V, Daneels G, de Strooper B, de Wit J, Verstreken P, Moechars D. Calafate S, et al. Among authors: verstreken p. Cell Rep. 2015 May 26;11(8):1176-83. doi: 10.1016/j.celrep.2015.04.043. Epub 2015 May 14. Cell Rep. 2015. PMID: 25981034 Free article.
Mitochondria Re-set Epilepsy.
Uytterhoeven V, Kaempf N, Verstreken P. Uytterhoeven V, et al. Among authors: verstreken p. Neuron. 2019 Jun 5;102(5):907-910. doi: 10.1016/j.neuron.2019.05.023. Neuron. 2019. PMID: 31170397 Free article.
Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation.
Largo-Barrientos P, Apóstolo N, Creemers E, Callaerts-Vegh Z, Swerts J, Davies C, McInnes J, Wierda K, De Strooper B, Spires-Jones T, de Wit J, Uytterhoeven V, Verstreken P. Largo-Barrientos P, et al. Among authors: verstreken p. Neuron. 2021 Mar 3;109(5):767-777.e5. doi: 10.1016/j.neuron.2020.12.016. Epub 2021 Jan 19. Neuron. 2021. PMID: 33472038 Free PMC article.
PIWIL1 protein power targets tau therapy.
Soukup SF, Verstreken P. Soukup SF, et al. Among authors: verstreken p. Nat Neurosci. 2014 Mar;17(3):334-5. doi: 10.1038/nn.3659. Nat Neurosci. 2014. PMID: 24569826 No abstract available.
133 results