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Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival.
Guilhamon P, Chesnelong C, Kushida MM, Nikolic A, Singhal D, MacLeod G, Madani Tonekaboni SA, Cavalli FM, Arlidge C, Rajakulendran N, Rastegar N, Hao X, Hassam R, Smith LJ, Whetstone H, Coutinho FJ, Nadorp B, Ellestad KI, Luchman HA, Chan JA, Shoichet MS, Taylor MD, Haibe-Kains B, Weiss S, Angers S, Gallo M, Dirks PB, Lupien M. Guilhamon P, et al. Elife. 2021 Jan 11;10:e64090. doi: 10.7554/eLife.64090. Elife. 2021. PMID: 33427645 Free PMC article.
Medulloblastoma subgroups remain stable across primary and metastatic compartments.
Wang X, Dubuc AM, Ramaswamy V, Mack S, Gendoo DM, Remke M, Wu X, Garzia L, Luu B, Cavalli F, Peacock J, López B, Skowron P, Zagzag D, Lyden D, Hoffman C, Cho YJ, Eberhart C, MacDonald T, Li XN, Van Meter T, Northcott PA, Haibe-Kains B, Hawkins C, Rutka JT, Bouffet E, Pfister SM, Korshunov A, Taylor MD. Wang X, et al. Acta Neuropathol. 2015 Mar;129(3):449-57. doi: 10.1007/s00401-015-1389-0. Epub 2015 Jan 21. Acta Neuropathol. 2015. PMID: 25689980 Free PMC article.
Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer.
Bailey SD, Desai K, Kron KJ, Mazrooei P, Sinnott-Armstrong NA, Treloar AE, Dowar M, Thu KL, Cescon DW, Silvester J, Yang SY, Wu X, Pezo RC, Haibe-Kains B, Mak TW, Bedard PL, Pugh TJ, Sallari RC, Lupien M. Bailey SD, et al. Nat Genet. 2016 Oct;48(10):1260-6. doi: 10.1038/ng.3650. Epub 2016 Aug 29. Nat Genet. 2016. PMID: 27571262 Free PMC article.
Predictive approaches for drug combination discovery in cancer.
Madani Tonekaboni SA, Soltan Ghoraie L, Manem VSK, Haibe-Kains B. Madani Tonekaboni SA, et al. Brief Bioinform. 2018 Mar 1;19(2):263-276. doi: 10.1093/bib/bbw104. Brief Bioinform. 2018. PMID: 27881431 Free PMC article. Review.
Tissue specificity of in vitro drug sensitivity.
Yao F, Madani Tonekaboni SA, Safikhani Z, Smirnov P, El-Hachem N, Freeman M, Manem VSK, Haibe-Kains B. Yao F, et al. J Am Med Inform Assoc. 2018 Feb 1;25(2):158-166. doi: 10.1093/jamia/ocx062. J Am Med Inform Assoc. 2018. PMID: 29016819 Free PMC article.
SIGN: similarity identification in gene expression.
Madani Tonekaboni SA, Manem VSK, El-Hachem N, Haibe-Kains B. Madani Tonekaboni SA, et al. Bioinformatics. 2019 Nov 1;35(22):4830-4833. doi: 10.1093/bioinformatics/btz485. Bioinformatics. 2019. PMID: 31198954 Free PMC article.
244 results