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The association between tumor mutational burden and prognosis is dependent on treatment context.
Valero C, Lee M, Hoen D, Wang J, Nadeem Z, Patel N, Postow MA, Shoushtari AN, Plitas G, Balachandran VP, Smith JJ, Crago AM, Long Roche KC, Kelly DW, Samstein RM, Rana S, Ganly I, Wong RJ, Hakimi AA, Berger MF, Zehir A, Solit DB, Ladanyi M, Riaz N, Chan TA, Seshan VE, Morris LGT. Valero C, et al. Among authors: seshan ve. Nat Genet. 2021 Jan;53(1):11-15. doi: 10.1038/s41588-020-00752-4. Epub 2021 Jan 4. Nat Genet. 2021. PMID: 33398197 Free PMC article.
Randomized phase II study of pulse erlotinib before or after carboplatin and paclitaxel in current or former smokers with advanced non-small-cell lung cancer.
Riely GJ, Rizvi NA, Kris MG, Milton DT, Solit DB, Rosen N, Senturk E, Azzoli CG, Brahmer JR, Sirotnak FM, Seshan VE, Fogle M, Ginsberg M, Miller VA, Rudin CM. Riely GJ, et al. Among authors: seshan ve. J Clin Oncol. 2009 Jan 10;27(2):264-70. doi: 10.1200/JCO.2008.17.4656. Epub 2008 Dec 1. J Clin Oncol. 2009. PMID: 19047285 Free PMC article. Clinical Trial.
Breast cancer methylomes establish an epigenomic foundation for metastasis.
Fang F, Turcan S, Rimner A, Kaufman A, Giri D, Morris LG, Shen R, Seshan V, Mo Q, Heguy A, Baylin SB, Ahuja N, Viale A, Massague J, Norton L, Vahdat LT, Moynahan ME, Chan TA. Fang F, et al. Sci Transl Med. 2011 Mar 23;3(75):75ra25. doi: 10.1126/scitranslmed.3001875. Sci Transl Med. 2011. PMID: 21430268 Free PMC article.
Integrative subtype discovery in glioblastoma using iCluster.
Shen R, Mo Q, Schultz N, Seshan VE, Olshen AB, Huse J, Ladanyi M, Sander C. Shen R, et al. Among authors: seshan ve. PLoS One. 2012;7(4):e35236. doi: 10.1371/journal.pone.0035236. Epub 2012 Apr 23. PLoS One. 2012. PMID: 22539962 Free PMC article.
Genomic investigation of etiologic heterogeneity: methodologic challenges.
Begg CB, Seshan VE, Zabor EC, Furberg H, Arora A, Shen R, Maranchie JK, Nielsen ME, Rathmell WK, Signoretti S, Tamboli P, Karam JA, Choueiri TK, Hakimi AA, Hsieh JJ. Begg CB, et al. Among authors: seshan ve. BMC Med Res Methodol. 2014 Dec 22;14:138. doi: 10.1186/1471-2288-14-138. BMC Med Res Methodol. 2014. PMID: 25532962 Free PMC article.
Mitochondrial DNA copy number variation across human cancers.
Reznik E, Miller ML, Şenbabaoğlu Y, Riaz N, Sarungbam J, Tickoo SK, Al-Ahmadie HA, Lee W, Seshan VE, Hakimi AA, Sander C. Reznik E, et al. Among authors: seshan ve. Elife. 2016 Feb 22;5:e10769. doi: 10.7554/eLife.10769. Elife. 2016. PMID: 26901439 Free PMC article.
Genomic landscape and evolution of metastatic chromophobe renal cell carcinoma.
Casuscelli J, Weinhold N, Gundem G, Wang L, Zabor EC, Drill E, Wang PI, Nanjangud GJ, Redzematovic A, Nargund AM, Manley BJ, Arcila ME, Donin NM, Cheville JC, Thompson RH, Pantuck AJ, Russo P, Cheng EH, Lee W, Tickoo SK, Ostrovnaya I, Creighton CJ, Papaemmanuil E, Seshan VE, Hakimi AA, Hsieh JJ. Casuscelli J, et al. Among authors: seshan ve. JCI Insight. 2017 Jun 15;2(12):e92688. doi: 10.1172/jci.insight.92688. eCollection 2017 Jun 15. JCI Insight. 2017. PMID: 28614790 Free PMC article.
138 results