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Preclinical and first-in-human-brain-cancer applications of [18F]poly (ADP-ribose) polymerase inhibitor PET/MR.
Young RJ, Demétrio De Souza França P, Pirovano G, Piotrowski AF, Nicklin PJ, Riedl CC, Schwartz J, Bale TA, Donabedian PL, Kossatz S, Burnazi EM, Roberts S, Lyashchenko SK, Miller AM, Moss NS, Fiasconaro M, Zhang Z, Mauguen A, Reiner T, Dunphy MP. Young RJ, et al. Among authors: lyashchenko sk. Neurooncol Adv. 2020 Sep 15;2(1):vdaa119. doi: 10.1093/noajnl/vdaa119. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 33392502 Free PMC article.
Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo.
Venneti S, Dunphy MP, Zhang H, Pitter KL, Zanzonico P, Campos C, Carlin SD, La Rocca G, Lyashchenko S, Ploessl K, Rohle D, Omuro AM, Cross JR, Brennan CW, Weber WA, Holland EC, Mellinghoff IK, Kung HF, Lewis JS, Thompson CB. Venneti S, et al. Sci Transl Med. 2015 Feb 11;7(274):274ra17. doi: 10.1126/scitranslmed.aaa1009. Sci Transl Med. 2015. PMID: 25673762 Free PMC article.
Biodistribution and Dosimetry of 18F-Meta-Fluorobenzylguanidine: A First-in-Human PET/CT Imaging Study of Patients with Neuroendocrine Malignancies.
Pandit-Taskar N, Zanzonico P, Staton KD, Carrasquillo JA, Reidy-Lagunes D, Lyashchenko S, Burnazi E, Zhang H, Lewis JS, Blasberg R, Larson SM, Weber WA, Modak S. Pandit-Taskar N, et al. J Nucl Med. 2018 Jan;59(1):147-153. doi: 10.2967/jnumed.117.193169. Epub 2017 Jul 13. J Nucl Med. 2018. PMID: 28705916 Free PMC article. Clinical Trial.
First-in-Human Human Epidermal Growth Factor Receptor 2-Targeted Imaging Using 89Zr-Pertuzumab PET/CT: Dosimetry and Clinical Application in Patients with Breast Cancer.
Ulaner GA, Lyashchenko SK, Riedl C, Ruan S, Zanzonico PB, Lake D, Jhaveri K, Zeglis B, Lewis JS, O'Donoghue JA. Ulaner GA, et al. Among authors: lyashchenko sk. J Nucl Med. 2018 Jun;59(6):900-906. doi: 10.2967/jnumed.117.202010. Epub 2017 Nov 16. J Nucl Med. 2018. PMID: 29146695 Free PMC article. Clinical Trial.
In Vivo PET Assay of Tumor Glutamine Flux and Metabolism: In-Human Trial of 18F-(2S,4R)-4-Fluoroglutamine.
Dunphy MPS, Harding JJ, Venneti S, Zhang H, Burnazi EM, Bromberg J, Omuro AM, Hsieh JJ, Mellinghoff IK, Staton K, Pressl C, Beattie BJ, Zanzonico PB, Gerecitano JF, Kelsen DP, Weber W, Lyashchenko SK, Kung HF, Lewis JS. Dunphy MPS, et al. Among authors: lyashchenko sk. Radiology. 2018 May;287(2):667-675. doi: 10.1148/radiol.2017162610. Epub 2018 Jan 31. Radiology. 2018. PMID: 29388903 Free PMC article. Clinical Trial.
Paradigms for Precision Medicine in Epichaperome Cancer Therapy.
Pillarsetty N, Jhaveri K, Taldone T, Caldas-Lopes E, Punzalan B, Joshi S, Bolaender A, Uddin MM, Rodina A, Yan P, Ku A, Ku T, Shah SK, Lyashchenko S, Burnazi E, Wang T, Lecomte N, Janjigian Y, Younes A, Batlevi CW, Guzman ML, Roboz GJ, Koziorowski J, Zanzonico P, Alpaugh ML, Corben A, Modi S, Norton L, Larson SM, Lewis JS, Chiosis G, Gerecitano JF, Dunphy MPS. Pillarsetty N, et al. Among authors: lyashchenko s. Cancer Cell. 2019 Nov 11;36(5):559-573.e7. doi: 10.1016/j.ccell.2019.09.007. Epub 2019 Oct 24. Cancer Cell. 2019. PMID: 31668946 Free PMC article.
First-in-Humans Trial of Dasatinib-Derivative Tracer for Tumor Kinase-Targeted PET.
Krebs S, Veach DR, Carter LM, Grkovski M, Fornier M, Mauro MJ, Voss MH, Danila DC, Burnazi E, Null M, Staton K, Pressl C, Beattie BJ, Zanzonico P, Weber WA, Lyashchenko SK, Lewis JS, Larson SM, Dunphy MPS. Krebs S, et al. Among authors: lyashchenko sk. J Nucl Med. 2020 Nov;61(11):1580-1587. doi: 10.2967/jnumed.119.234864. Epub 2020 Mar 13. J Nucl Med. 2020. PMID: 32169913 Free PMC article.
Safety and Feasibility of PARP1/2 Imaging with 18F-PARPi in Patients with Head and Neck Cancer.
Schöder H, França PDS, Nakajima R, Burnazi E, Roberts S, Brand C, Grkovski M, Mauguen A, Dunphy MP, Ghossein RA, Lyashchenko SK, Lewis JS, O'Donoghue JA, Ganly I, Patel SG, Lee NY, Reiner T. Schöder H, et al. Among authors: lyashchenko sk. Clin Cancer Res. 2020 Jul 1;26(13):3110-3116. doi: 10.1158/1078-0432.CCR-19-3484. Epub 2020 Apr 3. Clin Cancer Res. 2020. PMID: 32245901 Free PMC article. Clinical Trial.
49 results