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Immune checkpoint combinations from mouse to man.
Ai M, Curran MA. Ai M, et al. Among authors: curran ma. Cancer Immunol Immunother. 2015 Jul;64(7):885-92. doi: 10.1007/s00262-014-1650-8. Epub 2015 Jan 3. Cancer Immunol Immunother. 2015. PMID: 25555570 Free PMC article. Review.
Intratumoral CD40 activation and checkpoint blockade induces T cell-mediated eradication of melanoma in the brain.
Singh M, Vianden C, Cantwell MJ, Dai Z, Xiao Z, Sharma M, Khong H, Jaiswal AR, Faak F, Hailemichael Y, Janssen LME, Bharadwaj U, Curran MA, Diab A, Bassett RL, Tweardy DJ, Hwu P, Overwijk WW. Singh M, et al. Among authors: curran ma. Nat Commun. 2017 Nov 13;8(1):1447. doi: 10.1038/s41467-017-01572-7. Nat Commun. 2017. PMID: 29129918 Free PMC article.
Targeted hypoxia reduction restores T cell infiltration and sensitizes prostate cancer to immunotherapy.
Jayaprakash P, Ai M, Liu A, Budhani P, Bartkowiak T, Sheng J, Ager C, Nicholas C, Jaiswal AR, Sun Y, Shah K, Balasubramanyam S, Li N, Wang G, Ning J, Zal A, Zal T, Curran MA. Jayaprakash P, et al. Among authors: curran ma. J Clin Invest. 2018 Nov 1;128(11):5137-5149. doi: 10.1172/JCI96268. Epub 2018 Oct 15. J Clin Invest. 2018. PMID: 30188869 Free PMC article.
Tumor hypermetabolism confers resistance to immunotherapy.
Liu A, Curran MA. Liu A, et al. Among authors: curran ma. Semin Cancer Biol. 2020 Oct;65:155-163. doi: 10.1016/j.semcancer.2020.01.009. Epub 2020 Jan 23. Semin Cancer Biol. 2020. PMID: 31982512 Review.
Melanoma Evolves Complete Immunotherapy Resistance through the Acquisition of a Hypermetabolic Phenotype.
Jaiswal AR, Liu AJ, Pudakalakatti S, Dutta P, Jayaprakash P, Bartkowiak T, Ager CR, Wang ZQ, Reuben A, Cooper ZA, Ivan C, Ju Z, Nwajei F, Wang J, Davies MA, Davis RE, Wargo JA, Bhattacharya PK, Hong DS, Curran MA. Jaiswal AR, et al. Among authors: curran ma. Cancer Immunol Res. 2020 Nov;8(11):1365-1380. doi: 10.1158/2326-6066.CIR-19-0005. Epub 2020 Sep 11. Cancer Immunol Res. 2020. PMID: 32917656 Free PMC article.
LAG-3 expression on peripheral blood cells identifies patients with poorer outcomes after immune checkpoint blockade.
Shen R, Postow MA, Adamow M, Arora A, Hannum M, Maher C, Wong P, Curran MA, Hollmann TJ, Jia L, Al-Ahmadie H, Keegan N, Funt SA, Iyer G, Rosenberg JE, Bajorin DF, Chapman PB, Shoushtari AN, Betof AS, Momtaz P, Merghoub T, Wolchok JD, Panageas KS, Callahan MK. Shen R, et al. Among authors: curran ma. Sci Transl Med. 2021 Aug 25;13(608):eabf5107. doi: 10.1126/scitranslmed.abf5107. Sci Transl Med. 2021. PMID: 34433638 Free PMC article.
145 results