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Bispecific T cell-engager targeting oncofetal chondroitin sulfate induces complete tumor regression and protective immune memory in mice.
Skeltved N, Nordmaj MA, Berendtsen NT, Dagil R, Stormer EMR, Al-Nakouzi N, Jiang K, Aicher A, Heeschen C, Gustavsson T, Choudhary S, Gögenur I, Christensen JP, Theander TG, Daugaard M, Salanti A, Nielsen MA. Skeltved N, et al. Among authors: al nakouzi n. J Exp Clin Cancer Res. 2023 Apr 28;42(1):106. doi: 10.1186/s13046-023-02655-8. J Exp Clin Cancer Res. 2023. PMID: 37118819 Free PMC article.
Reformation of the chondroitin sulfate glycocalyx enables progression of AR-independent prostate cancer.
Al-Nakouzi N, Wang CK, Oo HZ, Nelepcu I, Lallous N, Spliid CB, Khazamipour N, Lo J, Truong S, Collins C, Hui D, Esfandnia S, Adomat H, Clausen TM, Gustavsson T, Choudhary S, Dagil R, Corey E, Wang Y, Chauchereau A, Fazli L, Esko JD, Salanti A, Nelson PS, Gleave ME, Daugaard M. Al-Nakouzi N, et al. Nat Commun. 2022 Aug 13;13(1):4760. doi: 10.1038/s41467-022-32530-7. Nat Commun. 2022. PMID: 35963852 Free PMC article.
Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells.
Wang CK, Nelepcu I, Hui D, Oo HZ, Truong S, Zhao S, Tahiry Z, Esfandnia S, Ghaidi F, Adomat H, Dagil R, Gustavsson T, Choudhary S, Salanti A, Sorensen PH, Al Nakouzi N, Daugaard M. Wang CK, et al. Among authors: al nakouzi n. Sci Rep. 2022 Feb 23;12(1):3075. doi: 10.1038/s41598-022-07025-6. Sci Rep. 2022. PMID: 35197518 Free PMC article.
Oncofetal Chondroitin Sulfate Is a Highly Expressed Therapeutic Target in Non-Small Cell Lung Cancer.
Oo HZ, Lohinai Z, Khazamipour N, Lo J, Kumar G, Pihl J, Adomat H, Nabavi N, Behmanesh H, Zhai B, Dagil R, Choudhary S, Gustavsson T, Clausen TM, Esko JD, Allen JW, Thompson MA, Tran NL, Moldvay J, Dome B, Salanti A, Al-Nakouzi N, Weiss GJ, Daugaard M. Oo HZ, et al. Among authors: al nakouzi n. Cancers (Basel). 2021 Sep 6;13(17):4489. doi: 10.3390/cancers13174489. Cancers (Basel). 2021. PMID: 34503301 Free PMC article.
Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28.
Müller I, Strozyk E, Schindler S, Beissert S, Oo HZ, Sauter T, Lucarelli P, Raeth S, Hausser A, Al Nakouzi N, Fazli L, Gleave ME, Liu H, Simon HU, Walczak H, Green DR, Bartek J, Daugaard M, Kulms D. Müller I, et al. Among authors: al nakouzi n. Mol Cell. 2020 Mar 5;77(5):970-984.e7. doi: 10.1016/j.molcel.2019.12.023. Epub 2020 Jan 22. Mol Cell. 2020. PMID: 31982308 Free PMC article.
Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models.
Nappi L, Aguda AH, Nakouzi NA, Lelj-Garolla B, Beraldi E, Lallous N, Thi M, Moore S, Fazli L, Battsogt D, Stief S, Ban F, Nguyen NT, Saxena N, Dueva E, Zhang F, Yamazaki T, Zoubeidi A, Cherkasov A, Brayer GD, Gleave M. Nappi L, et al. Among authors: nakouzi na. J Clin Invest. 2020 Feb 3;130(2):699-714. doi: 10.1172/JCI130819. J Clin Invest. 2020. PMID: 31845908 Free PMC article.
Regulation of eIF4F Translation Initiation Complex by the Peptidyl Prolyl Isomerase FKBP7 in Taxane-resistant Prostate Cancer.
Garrido MF, Martin NJ, Bertrand M, Gaudin C, Commo F, El Kalaany N, Al Nakouzi N, Fazli L, Del Nery E, Camonis J, Perez F, Lerondel S, Le Pape A, Compagno D, Gleave M, Loriot Y, Désaubry L, Vagner S, Fizazi K, Chauchereau A. Garrido MF, et al. Among authors: al nakouzi n. Clin Cancer Res. 2019 Jan 15;25(2):710-723. doi: 10.1158/1078-0432.CCR-18-0704. Epub 2018 Oct 15. Clin Cancer Res. 2019. PMID: 30322877
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