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SLC-0111 enaminone analogs, 3/4-(3-aryl-3-oxopropenyl) aminobenzenesulfonamides, as novel selective subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform IX.
Eldehna WM, Abo-Ashour MF, Berrino E, Vullo D, Ghabbour HA, Al-Rashood ST, Hassan GS, Alkahtani HM, Almehizia AA, Alharbi A, Abdel-Aziz HA, Supuran CT. Eldehna WM, et al. Among authors: alharbi a. Bioorg Chem. 2019 Mar;83:549-558. doi: 10.1016/j.bioorg.2018.11.014. Epub 2018 Nov 14. Bioorg Chem. 2019. PMID: 30471577
Novel Diamide-Based Benzenesulfonamides as Selective Carbonic Anhydrase IX Inhibitors Endowed with Antitumor Activity: Synthesis, Biological Evaluation and In Silico Insights.
Abdelrahman MA, Eldehna WM, Nocentini A, Bua S, Al-Rashood ST, Hassan GS, Bonardi A, Almehizia AA, Alkahtani HM, Alharbi A, Gratteri P, Supuran CT. Abdelrahman MA, et al. Among authors: alharbi a. Int J Mol Sci. 2019 May 20;20(10):2484. doi: 10.3390/ijms20102484. Int J Mol Sci. 2019. PMID: 31137489 Free PMC article.
Synthesis, biological evaluation and in silico studies with 4-benzylidene-2-phenyl-5(4H)-imidazolone-based benzenesulfonamides as novel selective carbonic anhydrase IX inhibitors endowed with anticancer activity.
Eldehna WM, Abdelrahman MA, Nocentini A, Bua S, Al-Rashood ST, Hassan GS, Bonardi A, Almehizia AA, Alkahtani HM, Alharbi A, Gratteri P, Supuran CT. Eldehna WM, et al. Among authors: alharbi a. Bioorg Chem. 2019 Sep;90:103102. doi: 10.1016/j.bioorg.2019.103102. Epub 2019 Jul 2. Bioorg Chem. 2019. PMID: 31299596
Development of 2-oindolin-3-ylidene-indole-3-carbohydrazide derivatives as novel apoptotic and anti-proliferative agents towards colorectal cancer cells.
Eldehna WM, Abo-Ashour MF, Al-Warhi T, Al-Rashood ST, Alharbi A, Ayyad RR, Al-Khayal K, Abdulla M, Abdel-Aziz HA, Ahmad R, El-Haggar R. Eldehna WM, et al. Among authors: alharbi a. J Enzyme Inhib Med Chem. 2021 Dec;36(1):319-328. doi: 10.1080/14756366.2020.1862100. J Enzyme Inhib Med Chem. 2021. PMID: 33345633 Free PMC article.
1,150 results