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Dual Pharmacological Targeting of HDACs and PDE5 Inhibits Liver Disease Progression in a Mouse Model of Biliary Inflammation and Fibrosis.
Claveria-Cabello A, Colyn L, Uriarte I, Latasa MU, Arechederra M, Herranz JM, Alvarez L, Urman JM, Martinez-Chantar ML, Banales JM, Sangro B, Rombouts K, Oyarzabal J, Marin JJG, Berasain C, Avila MA, Fernandez-Barrena MG. Claveria-Cabello A, et al. Among authors: rombouts k. Cancers (Basel). 2020 Dec 13;12(12):3748. doi: 10.3390/cancers12123748. Cancers (Basel). 2020. PMID: 33322158 Free PMC article.
Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma.
Bárcena-Varela M, Caruso S, Llerena S, Álvarez-Sola G, Uriarte I, Latasa MU, Urtasun R, Rebouissou S, Alvarez L, Jimenez M, Santamaría E, Rodriguez-Ortigosa C, Mazza G, Rombouts K, San José-Eneriz E, Rabal O, Agirre X, Iraburu M, Santos-Laso A, Banales JM, Zucman-Rossi J, Prósper F, Oyarzabal J, Berasain C, Ávila MA, Fernández-Barrena MG. Bárcena-Varela M, et al. Among authors: rombouts k. Hepatology. 2019 Feb;69(2):587-603. doi: 10.1002/hep.30168. Epub 2019 Jan 4. Hepatology. 2019. PMID: 30014490
CXCR7 contributes to the aggressive phenotype of cholangiocarcinoma cells.
Gentilini A, Caligiuri A, Raggi C, Rombouts K, Pinzani M, Lori G, Correnti M, Invernizzi P, Rovida E, Navari N, Di Matteo S, Alvaro D, Banales JM, Rodrigues P, Raschioni C, Donadon M, Di Tommaso L, Marra F. Gentilini A, et al. Among authors: rombouts k. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2246-2256. doi: 10.1016/j.bbadis.2019.04.020. Epub 2019 May 3. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 31059778 Free article.
Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis.
Barcena-Varela M, Paish H, Alvarez L, Uriarte I, Latasa MU, Santamaria E, Recalde M, Garate M, Claveria A, Colyn L, Arechederra M, Iraburu MJ, Milkiewicz M, Milkiewicz P, Sangro B, Robinson SM, French J, Pardo-Saganta A, Oyarzabal J, Prosper F, Rombouts K, Oakley F, Mann J, Berasain C, Avila MA, G Fernandez-Barrena M. Barcena-Varela M, et al. Among authors: rombouts k. Gut. 2021 Feb;70(2):388-400. doi: 10.1136/gutjnl-2019-320205. Epub 2020 Apr 23. Gut. 2021. PMID: 32327527
Ammonia Scavenging Prevents Progression of Fibrosis in Experimental Nonalcoholic Fatty Liver Disease.
De Chiara F, Thomsen KL, Habtesion A, Jones H, Davies N, Gracia-Sancho J, Manicardi N, Hall A, Andreola F, Paish HL, Reed LH, Watson AA, Leslie J, Oakley F, Rombouts K, Mookerjee RP, Mann J, Jalan R. De Chiara F, et al. Among authors: rombouts k. Hepatology. 2020 Mar;71(3):874-892. doi: 10.1002/hep.30890. Epub 2019 Oct 15. Hepatology. 2020. PMID: 31378982
Liver fibrosis: from the bench to clinical targets.
Pinzani M, Rombouts K. Pinzani M, et al. Among authors: rombouts k. Dig Liver Dis. 2004 Apr;36(4):231-42. doi: 10.1016/j.dld.2004.01.003. Dig Liver Dis. 2004. PMID: 15115333 Review.
Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease.
Becares N, Gage MC, Voisin M, Shrestha E, Martin-Gutierrez L, Liang N, Louie R, Pourcet B, Pello OM, Luong TV, Goñi S, Pichardo-Almarza C, Røberg-Larsen H, Diaz-Zuccarini V, Steffensen KR, O'Brien A, Garabedian MJ, Rombouts K, Treuter E, Pineda-Torra I. Becares N, et al. Among authors: rombouts k. Cell Rep. 2019 Jan 22;26(4):984-995.e6. doi: 10.1016/j.celrep.2018.12.094. Cell Rep. 2019. PMID: 30673619 Free PMC article.
91 results