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Antigen-driven PD-1+ TOX+ BHLHE40+ and PD-1+ TOX+ EOMES+ T lymphocytes regulate juvenile idiopathic arthritis in situ.
Maschmeyer P, Heinz GA, Skopnik CM, Lutter L, Mazzoni A, Heinrich F, von Stuckrad SL, Wirth LE, Tran CL, Riedel R, Lehmann K, Sakwa I, Cimaz R, Giudici F, Mall MA, Enghard P, Vastert B, Chang HD, Durek P, Annunziato F, van Wijk F, Radbruch A, Kallinich T, Mashreghi MF. Maschmeyer P, et al. Among authors: enghard p. Eur J Immunol. 2021 Apr;51(4):915-929. doi: 10.1002/eji.202048797. Epub 2021 Feb 2. Eur J Immunol. 2021. PMID: 33296081 Free article.
Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus.
Humrich JY, Morbach H, Undeutsch R, Enghard P, Rosenberger S, Weigert O, Kloke L, Heimann J, Gaber T, Brandenburg S, Scheffold A, Huehn J, Radbruch A, Burmester GR, Riemekasten G. Humrich JY, et al. Among authors: enghard p. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):204-9. doi: 10.1073/pnas.0903158107. Epub 2009 Dec 14. Proc Natl Acad Sci U S A. 2010. PMID: 20018660 Free PMC article.
Nuclear antigen-reactive CD4+ T cells expand in active systemic lupus erythematosus, produce effector cytokines, and invade the kidneys.
Abdirama D, Tesch S, Grießbach AS, von Spee-Mayer C, Humrich JY, Stervbo U, Babel N, Meisel C, Alexander T, Biesen R, Bacher P, Scheffold A, Eckardt KU, Hiepe F, Radbruch A, Burmester GR, Riemekasten G, Enghard P. Abdirama D, et al. Among authors: enghard p. Kidney Int. 2021 Jan;99(1):238-246. doi: 10.1016/j.kint.2020.05.051. Epub 2020 Jun 24. Kidney Int. 2021. PMID: 32592813 Free article.
Targeting CD38 with Daratumumab in Refractory Systemic Lupus Erythematosus.
Ostendorf L, Burns M, Durek P, Heinz GA, Heinrich F, Garantziotis P, Enghard P, Richter U, Biesen R, Schneider U, Knebel F, Burmester G, Radbruch A, Mei HE, Mashreghi MF, Hiepe F, Alexander T. Ostendorf L, et al. Among authors: enghard p. N Engl J Med. 2020 Sep 17;383(12):1149-1155. doi: 10.1056/NEJMoa2023325. N Engl J Med. 2020. PMID: 32937047
79 results