Sun X - Search Results

1

The new opportunities in medicinal chemistry of fourth-generation EGFR inhibitors to overcome C797S mutation.

He J, Zhou Z, Sun X, Yang Z, Zheng P, Xu S, Zhu W. He J, et al. Among authors: sun x. Eur J Med Chem. 2021 Jan 15;210:112995. doi: 10.1016/j.ejmech.2020.112995. Epub 2020 Nov 16. Eur J Med Chem. 2021. PMID: 33243531 Review.

2

Design, synthesis and biological evaluation of substituted 2-(thiophen-2-yl)-1,3,5-triazine derivatives as potential dual PI3Kα/mTOR inhibitors.

Zhang B, Zhang Q, Xiao Z, Sun X, Yang Z, Gu Q, Liu Z, Xie T, Jin Q, Zheng P, Xu S, Zhu W. Zhang B, et al. Among authors: sun x. Bioorg Chem. 2020 Jan;95:103525. doi: 10.1016/j.bioorg.2019.103525. Epub 2019 Dec 20. Bioorg Chem. 2020. PMID: 31887474

3

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors for the treatment of non-small cell lung cancer: a patent review (2014-present).

Sun X, Xu S, Yang Z, Zheng P, Zhu W. Sun X, et al. Expert Opin Ther Pat. 2021 Mar;31(3):223-238. doi: 10.1080/13543776.2021.1860210. Epub 2020 Dec 14. Expert Opin Ther Pat. 2021. PMID: 33315482 Review.

4

XS-2, a novel potent dual PI3K/mTOR inhibitor, exhibits high in vitro and in vivo anti-breast cancer activity and low toxicity with the potential to inhibit the invasion and migration of triple-negative breast cancer.

Xu S, Sun X, Luo L, Yang Y, Guo Q, Tang S, Jiang Z, Li Y, Han J, Gan W, Yang F, Zhang X, Liu Y, Sun C, He J, Liu M, Zuo D, Zhu W, Wu Y. Xu S, et al. Among authors: sun c, sun x. Biomed Pharmacother. 2022 Nov;155:113537. doi: 10.1016/j.biopha.2022.113537. Epub 2022 Sep 13. Biomed Pharmacother. 2022. PMID: 36113258 Free article.

5

Design, synthesis and pharmacological evaluation of 2-arylurea-1,3,5-triazine derivative (XIN-9): A novel potent dual PI3K/mTOR inhibitor for cancer therapy.

Sun X, Zhang B, Luo L, Yang Y, He B, Zhang Q, Wang L, Xu S, Zheng P, Zhu W. Sun X, et al. Bioorg Chem. 2022 Dec;129:106157. doi: 10.1016/j.bioorg.2022.106157. Epub 2022 Sep 27. Bioorg Chem. 2022. PMID: 36209563

6

Targeting autophagy enhances the anticancer effect of artemisinin and its derivatives.

Sun X, Yan P, Zou C, Wong YK, Shu Y, Lee YM, Zhang C, Yang ND, Wang J, Zhang J. Sun X, et al. Med Res Rev. 2019 Nov;39(6):2172-2193. doi: 10.1002/med.21580. Epub 2019 Apr 11. Med Res Rev. 2019. PMID: 30972803 Review.

7

Transcriptome profiling analysis reveals that ATP6V0E2 is involved in the lysosomal activation by anlotinib.

Sun X, Shu Y, Yan P, Huang H, Gao R, Xu M, Lu L, Tian J, Huang D, Zhang J. Sun X, et al. Cell Death Dis. 2020 Aug 24;11(8):702. doi: 10.1038/s41419-020-02904-0. Cell Death Dis. 2020. PMID: 32839434 Free PMC article.

8

Effects of brucine on vascular endothelial growth factor expression and microvessel density in a nude mouse model of bone metastasis due to breast cancer.

Li P, Zhang M, Ma WJ, Sun X, Jin FP. Li P, et al. Among authors: sun x. Chin J Integr Med. 2012 Aug;18(8):605-9. doi: 10.1007/s11655-012-1184-x. Epub 2012 Aug 2. Chin J Integr Med. 2012. PMID: 22855035

9

Parkin exerts the tumor-suppressive effect through targeting mitochondria.

Sun X, Ye G, Mai Y, Shu Y, Wang L, Zhang J. Sun X, et al. Med Res Rev. 2023 Jul;43(4):855-871. doi: 10.1002/med.21938. Epub 2023 Mar 14. Med Res Rev. 2023. PMID: 36916678 Review.

10

A Novel Benzofuran Derivative Moracin N Induces Autophagy and Apoptosis Through ROS Generation in Lung Cancer.

Gao C, Sun X, Wu Z, Yuan H, Han H, Huang H, Shu Y, Xu M, Gao R, Li S, Zhang J, Tian J. Gao C, et al. Among authors: sun x. Front Pharmacol. 2020 May 12;11:391. doi: 10.3389/fphar.2020.00391. eCollection 2020. Front Pharmacol. 2020. PMID: 32477104 Free PMC article.

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