Meanwell NA - Search Results

1

Discovery of BMS-986144, a Third-Generation, Pan-Genotype NS3/4A Protease Inhibitor for the Treatment of Hepatitis C Virus Infection.

Sun LQ, Mull E, D'Andrea S, Zheng B, Hiebert S, Gillis E, Bowsher M, Kandhasamy S, Baratam VR, Puttaswamy S, Pulicharla N, Vishwakrishnan S, Reddy S, Trivedi R, Sinha S, Sivaprasad S, Rao A, Desai S, Ghosh K, Anumula R, Kumar A, Rajamani R, Wang YK, Fang H, Mathur A, Rampulla R, Zvyaga TA, Mosure K, Jenkins S, Falk P, Tagore DM, Chen C, Rendunchintala K, Loy J, Meanwell NA, McPhee F, Scola PM. Sun LQ, et al. Among authors: meanwell na. J Med Chem. 2020 Dec 10;63(23):14740-14760. doi: 10.1021/acs.jmedchem.0c01296. Epub 2020 Nov 23. J Med Chem. 2020. PMID: 33226226

2

Inhibitors of blood platelet cAMP phosphodiesterase. 2. Structure-activity relationships associated with 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones substituted with functionalized side chains.

Meanwell NA, Pearce BC, Roth HR, Smith EC, Wedding DL, Wright JJ, Buchanan JO, Baryla UM, Gamberdella M, Gillespie E, et al. Meanwell NA, et al. J Med Chem. 1992 Jul 10;35(14):2672-87. doi: 10.1021/jm00092a019. J Med Chem. 1992. PMID: 1321910

3

Inhibitors of blood platelet cAMP phosphodiesterase. 3. 1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-one derivatives with enhanced aqueous solubility.

Meanwell NA, Dennis RD, Roth HR, Rosenfeld MJ, Smith EC, Wright JJ, Buchanan JO, Brassard CL, Gamberdella M, Gillespie E, et al. Meanwell NA, et al. J Med Chem. 1992 Jul 10;35(14):2688-96. doi: 10.1021/jm00092a020. J Med Chem. 1992. PMID: 1321911

4

Structure-activity relationships associated with 3,4,5-triphenyl-1H-pyrazole-1-nonanoic acid, a nonprostanoid prostacyclin mimetic.

Meanwell NA, Rosenfeld MJ, Wright JJ, Brassard CL, Buchanan JO, Federici ME, Fleming JS, Seiler SM. Meanwell NA, et al. J Med Chem. 1992 Jan 24;35(2):389-97. doi: 10.1021/jm00080a028. J Med Chem. 1992. PMID: 1370696

5

Nonprostanoid prostacyclin mimetics. 2. 4,5-Diphenyloxazole derivatives.

Meanwell NA, Rosenfeld MJ, Trehan AK, Wright JJ, Brassard CL, Buchanan JO, Federici ME, Fleming JS, Gamberdella M, Zavoico GB, et al. Meanwell NA, et al. J Med Chem. 1992 Sep 18;35(19):3483-97. doi: 10.1021/jm00097a006. J Med Chem. 1992. PMID: 1404230

6

Nonprostanoid prostacyclin mimetics. 3. Structural variations of the diphenyl heterocycle moiety.

Meanwell NA, Rosenfeld MJ, Trehan AK, Romine JL, Wright JJ, Brassard CL, Buchanan JO, Federici ME, Fleming JS, Gamberdella M, et al. Meanwell NA, et al. J Med Chem. 1992 Sep 18;35(19):3498-512. doi: 10.1021/jm00097a007. J Med Chem. 1992. PMID: 1404231

7

1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.

Meanwell NA, Roth HR, Smith EC, Wedding DL, Wright JJ, Fleming JS, Gillespie E. Meanwell NA, et al. J Med Chem. 1991 Sep;34(9):2906-16. doi: 10.1021/jm00113a033. J Med Chem. 1991. PMID: 1654430

8

Nonprostanoid prostacyclin mimetics. 5. Structure-activity relationships associated with [3-[4-(4,5-diphenyl-2-oxazolyl)-5- oxazolyl]phenoxy]acetic acid.

Meanwell NA, Romine JL, Rosenfeld MJ, Martin SW, Trehan AK, Wright JJ, Malley MF, Gougoutas JZ, Brassard CL, Buchanan JO, et al. Meanwell NA, et al. J Med Chem. 1993 Nov 26;36(24):3884-903. doi: 10.1021/jm00076a018. J Med Chem. 1993. PMID: 7504734

9

Azetidin-2-one derivatives as inhibitors of thrombin.

Han WT, Trehan AK, Wright JJ, Federici ME, Seiler SM, Meanwell NA. Han WT, et al. Among authors: meanwell na. Bioorg Med Chem. 1995 Aug;3(8):1123-43. doi: 10.1016/0968-0896(95)00101-l. Bioorg Med Chem. 1995. PMID: 7582985

10

Active site-directed thrombin inhibitors--II. Studies related to arginine/guanidine bioisosteres.

St Laurent DR, Balasubramanian N, Han WT, Trehan A, Federici ME, Meanwell NA, Wright JJ, Seiler SM. St Laurent DR, et al. Among authors: meanwell na. Bioorg Med Chem. 1995 Aug;3(8):1145-56. doi: 10.1016/0968-0896(95)00103-n. Bioorg Med Chem. 1995. PMID: 7582986

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