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Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer.
Siddiqui MA, Gollavilli PN, Ramesh V, Parma B, Schwab A, Vazakidou ME, Natesan R, Saatci O, Rapa I, Bironzo P, Schuhwerk H, Asangani IA, Sahin O, Volante M, Ceppi P. Siddiqui MA, et al. Among authors: ceppi p. Br J Cancer. 2021 Jan;124(1):281-289. doi: 10.1038/s41416-020-01095-x. Epub 2020 Oct 7. Br J Cancer. 2021. PMID: 33024270 Free PMC article.
Propionate reinforces epithelial identity and reduces aggressiveness of lung carcinoma.
Ramesh V, Gollavilli PN, Pinna L, Siddiqui MA, Turtos AM, Napoli F, Antonelli Y, Leal-Egaña A, Havelund JF, Jakobsen ST, Boiteux EL, Volante M, Faergeman NJ, Jensen ON, Siersbaek R, Somyajit K, Ceppi P. Ramesh V, et al. Among authors: ceppi p. EMBO Mol Med. 2023 Dec 7;15(12):e17836. doi: 10.15252/emmm.202317836. Epub 2023 Sep 28. EMBO Mol Med. 2023. PMID: 37766669 Free PMC article.
A non-proliferative role of pyrimidine metabolism in cancer.
Siddiqui A, Ceppi P. Siddiqui A, et al. Among authors: ceppi p. Mol Metab. 2020 May;35:100962. doi: 10.1016/j.molmet.2020.02.005. Epub 2020 Feb 13. Mol Metab. 2020. PMID: 32244187 Free PMC article. Review.
Metabolic impairment of non-small cell lung cancers by mitochondrial HSPD1 targeting.
Parma B, Ramesh V, Gollavilli PN, Siddiqui A, Pinna L, Schwab A, Marschall S, Zhang S, Pilarsky C, Napoli F, Volante M, Urbanczyk S, Mielenz D, Schrøder HD, Stemmler M, Wurdak H, Ceppi P. Parma B, et al. Among authors: ceppi p. J Exp Clin Cancer Res. 2021 Aug 7;40(1):248. doi: 10.1186/s13046-021-02049-8. J Exp Clin Cancer Res. 2021. PMID: 34364401 Free PMC article.
The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response.
Schuhwerk H, Kleemann J, Gupta P, van Roey R, Armstark I, Kreileder M, Feldker N, Ramesh V, Hajjaj Y, Fuchs K, Mahapatro M, Hribersek M, Volante M, Groenewoud A, Engel FB, Ceppi P, Eckstein M, Hartmann A, Müller F, Kroll T, Stemmler MP, Brabletz S, Brabletz T. Schuhwerk H, et al. Among authors: ceppi p. Cell Rep. 2022 Dec 13;41(11):111819. doi: 10.1016/j.celrep.2022.111819. Cell Rep. 2022. PMID: 36516781 Free article.
Roflumilast inhibits tumor growth and migration in STK11/LKB1 deficient pancreatic cancer.
Zhang S, Yun D, Yang H, Eckstein M, Elbait GD, Zhou Y, Lu Y, Yang H, Zhang J, Dörflein I, Britzen-Laurent N, Pfeffer S, Stemmler MP, Dahl A, Mukhopadhyay D, Chang D, He H, Zeng S, Lan B, Frey B, Hampel C, Lentsch E, Gollavilli PN, Büttner C, Ekici AB, Biankin A, Schneider-Stock R, Ceppi P, Grützmann R, Pilarsky C. Zhang S, et al. Among authors: ceppi p. Cell Death Discov. 2024 Mar 9;10(1):124. doi: 10.1038/s41420-024-01890-y. Cell Death Discov. 2024. PMID: 38461159 Free PMC article.
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