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Page 1
A Bioengineered Neuregulin-Hydrogel Therapy Reduces Scar Size and Enhances Post-Infarct Ventricular Contractility in an Ovine Large Animal Model.
Cohen JE, Goldstone AB, Wang H, Purcell BP, Shudo Y, MacArthur JW, Steele AN, Paulsen MJ, Edwards BB, Aribeana CN, Cheung NC, Burdick JA, Woo YJ. Cohen JE, et al. Among authors: edwards bb. J Cardiovasc Dev Dis. 2020 Nov 17;7(4):53. doi: 10.3390/jcdd7040053. J Cardiovasc Dev Dis. 2020. PMID: 33212844 Free PMC article.
A bioengineered hydrogel system enables targeted and sustained intramyocardial delivery of neuregulin, activating the cardiomyocyte cell cycle and enhancing ventricular function in a murine model of ischemic cardiomyopathy.
Cohen JE, Purcell BP, MacArthur JW Jr, Mu A, Shudo Y, Patel JB, Brusalis CM, Trubelja A, Fairman AS, Edwards BB, Davis MS, Hung G, Hiesinger W, Atluri P, Margulies KB, Burdick JA, Woo YJ. Cohen JE, et al. Among authors: edwards bb. Circ Heart Fail. 2014 Jul;7(4):619-26. doi: 10.1161/CIRCHEARTFAILURE.113.001273. Epub 2014 Jun 5. Circ Heart Fail. 2014. PMID: 24902740 Free PMC article.
Preclinical evaluation of the engineered stem cell chemokine stromal cell-derived factor 1α analog in a translational ovine myocardial infarction model.
Macarthur JW Jr, Cohen JE, McGarvey JR, Shudo Y, Patel JB, Trubelja A, Fairman AS, Edwards BB, Hung G, Hiesinger W, Goldstone AB, Atluri P, Wilensky RL, Pilla JJ, Gorman JH 3rd, Gorman RC, Woo YJ. Macarthur JW Jr, et al. Among authors: edwards bb. Circ Res. 2014 Feb 14;114(4):650-9. doi: 10.1161/CIRCRESAHA.114.302884. Epub 2013 Dec 23. Circ Res. 2014. PMID: 24366171 Free PMC article.
A Tissue-Engineered Chondrocyte Cell Sheet Induces Extracellular Matrix Modification to Enhance Ventricular Biomechanics and Attenuate Myocardial Stiffness in Ischemic Cardiomyopathy.
Shudo Y, Cohen JE, MacArthur JW, Goldstone AB, Otsuru S, Trubelja A, Patel J, Edwards BB, Hung G, Fairman AS, Brusalis C, Hiesinger W, Atluri P, Hiraoka A, Miyagawa S, Sawa Y, Woo YJ. Shudo Y, et al. Among authors: edwards bb. Tissue Eng Part A. 2015 Oct;21(19-20):2515-25. doi: 10.1089/ten.TEA.2014.0155. Epub 2015 Sep 18. Tissue Eng Part A. 2015. PMID: 26154752 Free PMC article.
A novel protein-engineered hepatocyte growth factor analog released via a shear-thinning injectable hydrogel enhances post-infarction ventricular function.
Steele AN, Cai L, Truong VN, Edwards BB, Goldstone AB, Eskandari A, Mitchell AC, Marquardt LM, Foster AA, Cochran JR, Heilshorn SC, Woo YJ. Steele AN, et al. Among authors: edwards bb. Biotechnol Bioeng. 2017 Oct;114(10):2379-2389. doi: 10.1002/bit.26345. Epub 2017 Jun 29. Biotechnol Bioeng. 2017. PMID: 28574594 Free PMC article.
An innovative biologic system for photon-powered myocardium in the ischemic heart.
Cohen JE, Goldstone AB, Paulsen MJ, Shudo Y, Steele AN, Edwards BB, Patel JB, MacArthur JW Jr, Hopkins MS, Burnett CE, Jaatinen KJ, Thakore AD, Farry JM, Truong VN, Bourdillon AT, Stapleton LM, Eskandari A, Fairman AS, Hiesinger W, Esipova TV, Patrick WL, Ji K, Shizuru JA, Woo YJ. Cohen JE, et al. Among authors: edwards bb. Sci Adv. 2017 Jun 14;3(6):e1603078. doi: 10.1126/sciadv.1603078. eCollection 2017 Jun. Sci Adv. 2017. PMID: 28630913 Free PMC article.
Layered smooth muscle cell-endothelial progenitor cell sheets derived from the bone marrow augment postinfarction ventricular function.
Shudo Y, Goldstone AB, Cohen JE, Patel JB, Hopkins MS, Steele AN, Edwards BB, Kawamura M, Miyagawa S, Sawa Y, Woo YJ. Shudo Y, et al. Among authors: edwards bb. J Thorac Cardiovasc Surg. 2017 Sep;154(3):955-963. doi: 10.1016/j.jtcvs.2017.04.081. Epub 2017 May 24. J Thorac Cardiovasc Surg. 2017. PMID: 28651946 Free PMC article.
Tissue-engineered smooth muscle cell and endothelial progenitor cell bi-level cell sheets prevent progression of cardiac dysfunction, microvascular dysfunction, and interstitial fibrosis in a rodent model of type 1 diabetes-induced cardiomyopathy.
Kawamura M, Paulsen MJ, Goldstone AB, Shudo Y, Wang H, Steele AN, Stapleton LM, Edwards BB, Eskandari A, Truong VN, Jaatinen KJ, Ingason AB, Miyagawa S, Sawa Y, Woo YJ. Kawamura M, et al. Among authors: edwards bb. Cardiovasc Diabetol. 2017 Nov 2;16(1):142. doi: 10.1186/s12933-017-0625-4. Cardiovasc Diabetol. 2017. PMID: 29096622 Free PMC article.
Angiogenesis precedes cardiomyocyte migration in regenerating mammalian hearts.
Ingason AB, Goldstone AB, Paulsen MJ, Thakore AD, Truong VN, Edwards BB, Eskandari A, Bollig T, Steele AN, Woo YJ. Ingason AB, et al. Among authors: edwards bb. J Thorac Cardiovasc Surg. 2018 Mar;155(3):1118-1127.e1. doi: 10.1016/j.jtcvs.2017.08.127. Epub 2017 Nov 29. J Thorac Cardiovasc Surg. 2018. PMID: 29452461 Free PMC article.
34 results