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A Bioengineered Neuregulin-Hydrogel Therapy Reduces Scar Size and Enhances Post-Infarct Ventricular Contractility in an Ovine Large Animal Model.
Cohen JE, Goldstone AB, Wang H, Purcell BP, Shudo Y, MacArthur JW, Steele AN, Paulsen MJ, Edwards BB, Aribeana CN, Cheung NC, Burdick JA, Woo YJ. Cohen JE, et al. Among authors: burdick ja. J Cardiovasc Dev Dis. 2020 Nov 17;7(4):53. doi: 10.3390/jcdd7040053. J Cardiovasc Dev Dis. 2020. PMID: 33212844 Free PMC article.
Injectable acellular hydrogels for cardiac repair.
Tous E, Purcell B, Ifkovits JL, Burdick JA. Tous E, et al. Among authors: burdick ja. J Cardiovasc Transl Res. 2011 Oct;4(5):528-42. doi: 10.1007/s12265-011-9291-1. Epub 2011 Jun 28. J Cardiovasc Transl Res. 2011. PMID: 21710332 Review.
Sustained release of engineered stromal cell-derived factor 1-α from injectable hydrogels effectively recruits endothelial progenitor cells and preserves ventricular function after myocardial infarction.
MacArthur JW Jr, Purcell BP, Shudo Y, Cohen JE, Fairman A, Trubelja A, Patel J, Hsiao P, Yang E, Lloyd K, Hiesinger W, Atluri P, Burdick JA, Woo YJ. MacArthur JW Jr, et al. Among authors: burdick ja. Circulation. 2013 Sep 10;128(11 Suppl 1):S79-86. doi: 10.1161/CIRCULATIONAHA.112.000343. Circulation. 2013. PMID: 24030424 Free PMC article.
Local hydrogel release of recombinant TIMP-3 attenuates adverse left ventricular remodeling after experimental myocardial infarction.
Eckhouse SR, Purcell BP, McGarvey JR, Lobb D, Logdon CB, Doviak H, O'Neill JW, Shuman JA, Novack CP, Zellars KN, Pettaway S, Black RA, Khakoo A, Lee T, Mukherjee R, Gorman JH, Gorman RC, Burdick JA, Spinale FG. Eckhouse SR, et al. Among authors: burdick ja. Sci Transl Med. 2014 Feb 12;6(223):223ra21. doi: 10.1126/scitranslmed.3007244. Sci Transl Med. 2014. PMID: 24523321 Free PMC article.
Injectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibition.
Purcell BP, Lobb D, Charati MB, Dorsey SM, Wade RJ, Zellars KN, Doviak H, Pettaway S, Logdon CB, Shuman JA, Freels PD, Gorman JH 3rd, Gorman RC, Spinale FG, Burdick JA. Purcell BP, et al. Among authors: burdick ja. Nat Mater. 2014 Jun;13(6):653-61. doi: 10.1038/nmat3922. Epub 2014 Mar 30. Nat Mater. 2014. PMID: 24681647 Free PMC article.
A bioengineered hydrogel system enables targeted and sustained intramyocardial delivery of neuregulin, activating the cardiomyocyte cell cycle and enhancing ventricular function in a murine model of ischemic cardiomyopathy.
Cohen JE, Purcell BP, MacArthur JW Jr, Mu A, Shudo Y, Patel JB, Brusalis CM, Trubelja A, Fairman AS, Edwards BB, Davis MS, Hung G, Hiesinger W, Atluri P, Margulies KB, Burdick JA, Woo YJ. Cohen JE, et al. Among authors: burdick ja. Circ Heart Fail. 2014 Jul;7(4):619-26. doi: 10.1161/CIRCHEARTFAILURE.113.001273. Epub 2014 Jun 5. Circ Heart Fail. 2014. PMID: 24902740 Free PMC article.
Injectable shear-thinning hydrogels used to deliver endothelial progenitor cells, enhance cell engraftment, and improve ischemic myocardium.
Gaffey AC, Chen MH, Venkataraman CM, Trubelja A, Rodell CB, Dinh PV, Hung G, MacArthur JW, Soopan RV, Burdick JA, Atluri P. Gaffey AC, et al. Among authors: burdick ja. J Thorac Cardiovasc Surg. 2015 Nov;150(5):1268-76. doi: 10.1016/j.jtcvs.2015.07.035. Epub 2015 Jul 17. J Thorac Cardiovasc Surg. 2015. PMID: 26293548 Free PMC article.
333 results