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A distinct subset of FcγRI-expressing Th1 cells exert antibody-mediated cytotoxic activity.
Rasoulouniriana D, Santana-Magal N, Gutwillig A, Farhat-Younis L, Wine Y, Saperia C, Tal L, Gutman H, Tsivian A, Brenner R, Bandora EA, Reticker-Flynn NE, Rider P, Carmi Y. Rasoulouniriana D, et al. Among authors: carmi y. J Clin Invest. 2019 Oct 1;129(10):4151-4164. doi: 10.1172/JCI127590. J Clin Invest. 2019. PMID: 31449054 Free PMC article.
In vivo engineered B cells secrete high titers of broadly neutralizing anti-HIV antibodies in mice.
Nahmad AD, Lazzarotto CR, Zelikson N, Kustin T, Tenuta M, Huang D, Reuveni I, Nataf D, Raviv Y, Horovitz-Fried M, Dotan I, Carmi Y, Rosin-Arbesfeld R, Nemazee D, Voss JE, Stern A, Tsai SQ, Barzel A. Nahmad AD, et al. Among authors: carmi y. Nat Biotechnol. 2022 Aug;40(8):1241-1249. doi: 10.1038/s41587-022-01328-9. Epub 2022 Jun 9. Nat Biotechnol. 2022. PMID: 35681059 Free PMC article.
Immune-stimulating antibody conjugates elicit robust myeloid activation and durable antitumor immunity.
Ackerman SE, Pearson CI, Gregorio JD, Gonzalez JC, Kenkel JA, Hartmann FJ, Luo A, Ho PY, LeBlanc H, Blum LK, Kimmey SC, Luo A, Nguyen ML, Paik JC, Sheu LY, Ackerman B, Lee A, Li H, Melrose J, Laura RP, Ramani VC, Henning KA, Jackson DY, Safina BS, Yonehiro G, Devens BH, Carmi Y, Chapin SJ, Bendall SC, Kowanetz M, Dornan D, Engleman EG, Alonso MN. Ackerman SE, et al. Among authors: carmi y. Nat Cancer. 2021 Jan;2(1):18-33. doi: 10.1038/s43018-020-00136-x. Epub 2020 Dec 7. Nat Cancer. 2021. PMID: 35121890 Free PMC article.
T Cells Expressing a Modified FcγRI Exert Antibody-Dependent Cytotoxicity and Overcome the Limitations of CAR T-cell Therapy against Solid Tumors.
Rasoulouniriana D, Santana-Magal N, Gutwillig A, Farhat-Younis L, Tal L, Amar S, Milyavsky M, Muddineni SSNA, Solomon N, Shpilt H, Dotan S, Pilpel N, Waskow C, Feinmesser M, Rider P, Carmi Y. Rasoulouniriana D, et al. Among authors: carmi y. Cancer Immunol Res. 2023 Jun 2;11(6):792-809. doi: 10.1158/2326-6066.CIR-22-0423. Cancer Immunol Res. 2023. PMID: 37070661 Free PMC article.
52 results