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TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages.
Alzheimers Res Ther. 2020 Nov 16;12(1):151. doi: 10.1186/s13195-020-00709-z.
Alzheimers Res Ther. 2020.
PMID: 33198789
Free PMC article.
Microglial inflammation and phagocytosis in Alzheimer's disease: Potential therapeutic targets.
Nizami S, Hall-Roberts H, Warrier S, Cowley SA, Di Daniel E.
Nizami S, et al. Among authors: hall roberts h.
Br J Pharmacol. 2019 Sep;176(18):3515-3532. doi: 10.1111/bph.14618. Epub 2019 May 11.
Br J Pharmacol. 2019.
PMID: 30740661
Free PMC article.
Review.
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In vitro Quantitative Imaging Assay for Phagocytosis of Dead Neuroblastoma Cells by iPSC-Macrophages.
Hall-Roberts H, Di Daniel E, James WS, Davis JB, Cowley SA.
Hall-Roberts H, et al.
J Vis Exp. 2021 Feb 14;(168). doi: 10.3791/62217.
J Vis Exp. 2021.
PMID: 33645588
Item in Clipboard
PLCγ2 regulates TREM2 signalling and integrin-mediated adhesion and migration of human iPSC-derived macrophages.
Obst J, Hall-Roberts HL, Smith TB, Kreuzer M, Magno L, Di Daniel E, Davis JB, Mead E.
Obst J, et al. Among authors: hall roberts hl.
Sci Rep. 2021 Oct 6;11(1):19842. doi: 10.1038/s41598-021-96144-7.
Sci Rep. 2021.
PMID: 34615897
Free PMC article.
Item in Clipboard
Human iPSC-derived glia models for the study of neuroinflammation.
Stöberl N, Maguire E, Salis E, Shaw B, Hall-Roberts H.
Stöberl N, et al. Among authors: hall roberts h.
J Neuroinflammation. 2023 Oct 10;20(1):231. doi: 10.1186/s12974-023-02919-2.
J Neuroinflammation. 2023.
PMID: 37817184
Free PMC article.
Review.
Item in Clipboard
Assaying Microglia Functions In Vitro.
Maguire E, Connor-Robson N, Shaw B, O'Donoghue R, Stöberl N, Hall-Roberts H.
Maguire E, et al. Among authors: hall roberts h.
Cells. 2022 Oct 28;11(21):3414. doi: 10.3390/cells11213414.
Cells. 2022.
PMID: 36359810
Free PMC article.
Review.
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Mutant huntingtin confers cell-autonomous phenotypes on Huntington's disease iPSC-derived microglia.
Stöberl N, Donaldson J, Binda CS, McAllister B, Hall-Roberts H, Jones L, Massey TH, Allen ND.
Stöberl N, et al. Among authors: hall roberts h.
Sci Rep. 2023 Nov 22;13(1):20477. doi: 10.1038/s41598-023-46852-z.
Sci Rep. 2023.
PMID: 37993517
Free PMC article.
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