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Disease progression of human SOD1 (G93A) transgenic ALS model rats.
Matsumoto A, Okada Y, Nakamichi M, Nakamura M, Toyama Y, Sobue G, Nagai M, Aoki M, Itoyama Y, Okano H. Matsumoto A, et al. Among authors: nagai m. J Neurosci Res. 2006 Jan;83(1):119-33. doi: 10.1002/jnr.20708. J Neurosci Res. 2006. PMID: 16342121
I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3β signaling pathway.
Ohta E, Nihira T, Uchino A, Imaizumi Y, Okada Y, Akamatsu W, Takahashi K, Hayakawa H, Nagai M, Ohyama M, Ryo M, Ogino M, Murayama S, Takashima A, Nishiyama K, Mizuno Y, Mochizuki H, Obata F, Okano H. Ohta E, et al. Among authors: nagai m. Hum Mol Genet. 2015 Sep 1;24(17):4879-900. doi: 10.1093/hmg/ddv212. Epub 2015 Jun 8. Hum Mol Genet. 2015. PMID: 26056228
Induced pluripotent stem cell-based Drug Repurposing for Amyotrophic lateral sclerosis Medicine (iDReAM) study: protocol for a phase I dose escalation study of bosutinib for amyotrophic lateral sclerosis patients.
Imamura K, Izumi Y, Banno H, Uozumi R, Morita S, Egawa N, Ayaki T, Nagai M, Nishiyama K, Watanabe Y, Hanajima R, Oki R, Fujita K, Takahashi N, Ikeda T, Shimizu A, Morinaga A, Hirohashi T, Fujii Y, Takahashi R, Inoue H. Imamura K, et al. Among authors: nagai m. BMJ Open. 2019 Dec 2;9(12):e033131. doi: 10.1136/bmjopen-2019-033131. BMJ Open. 2019. PMID: 31796494 Free PMC article.
Enhanced accumulation of phosphorylated alpha-synuclein in double transgenic mice expressing mutant beta-amyloid precursor protein and presenilin-1.
Kurata T, Kawarabayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y, Nagai M, Ikeda M, Matsubara E, Westaway D, Hyslop PS, Harigaya Y, Kamiya T, Shoji M, Abe K. Kurata T, et al. Among authors: nagai m. J Neurosci Res. 2007 Aug 1;85(10):2246-52. doi: 10.1002/jnr.21352. J Neurosci Res. 2007. PMID: 17526016
Increased autophagy in transgenic mice with a G93A mutant SOD1 gene.
Morimoto N, Nagai M, Ohta Y, Miyazaki K, Kurata T, Morimoto M, Murakami T, Takehisa Y, Ikeda Y, Kamiya T, Abe K. Morimoto N, et al. Among authors: nagai m. Brain Res. 2007 Sep 5;1167:112-7. doi: 10.1016/j.brainres.2007.06.045. Epub 2007 Jul 7. Brain Res. 2007. PMID: 17689501
2,170 results