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Maintained memory and long-term potentiation in a mouse model of Alzheimer's disease with both amyloid pathology and human tau.
Eur J Neurosci. 2021 Jan;53(2):637-648. doi: 10.1111/ejn.14918. Epub 2020 Aug 17.
Eur J Neurosci. 2021.
PMID: 33169893
Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease.
Pickett EK, Herrmann AG, McQueen J, Abt K, Dando O, Tulloch J, Jain P, Dunnett S, Sohrabi S, Fjeldstad MP, Calkin W, Murison L, Jackson RJ, Tzioras M, Stevenson A, d'Orange M, Hooley M, Davies C, Colom-Cadena M, Anton-Fernandez A, King D, Oren I, Rose J, McKenzie CA, Allison E, Smith C, Hardt O, Henstridge CM, Hardingham GE, Spires-Jones TL.
Pickett EK, et al.
Cell Rep. 2019 Dec 10;29(11):3592-3604.e5. doi: 10.1016/j.celrep.2019.11.044.
Cell Rep. 2019.
PMID: 31825838
Free PMC article.
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Non-Fibrillar Oligomeric Amyloid-β within Synapses.
Pickett EK, Koffie RM, Wegmann S, Henstridge CM, Herrmann AG, Colom-Cadena M, Lleo A, Kay KR, Vaught M, Soberman R, Walsh DM, Hyman BT, Spires-Jones TL.
Pickett EK, et al.
J Alzheimers Dis. 2016 May 30;53(3):787-800. doi: 10.3233/JAD-160007.
J Alzheimers Dis. 2016.
PMID: 27258414
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Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer's disease.
Pickett EK, Henstridge CM, Allison E, Pitstick R, Pooler A, Wegmann S, Carlson G, Hyman BT, Spires-Jones TL.
Pickett EK, et al.
Synapse. 2017 Jun;71(6):e21965. doi: 10.1002/syn.21965. Epub 2017 Mar 6.
Synapse. 2017.
PMID: 28196395
Free PMC article.
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Antidiabetic Polypill Improves Central Pathology and Cognitive Impairment in a Mixed Model of Alzheimer's Disease and Type 2 Diabetes.
Infante-Garcia C, Ramos-Rodriguez JJ, Hierro-Bujalance C, Ortegon E, Pickett E, Jackson R, Hernandez-Pacho F, Spires-Jones T, Garcia-Alloza M.
Infante-Garcia C, et al.
Mol Neurobiol. 2018 Jul;55(7):6130-6144. doi: 10.1007/s12035-017-0825-7. Epub 2017 Dec 9.
Mol Neurobiol. 2018.
PMID: 29224179
Free article.
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Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer's disease.
Pickett EK, Rose J, McCrory C, McKenzie CA, King D, Smith C, Gillingwater TH, Henstridge CM, Spires-Jones TL.
Pickett EK, et al.
Acta Neuropathol. 2018 Nov;136(5):747-757. doi: 10.1007/s00401-018-1903-2. Epub 2018 Sep 6.
Acta Neuropathol. 2018.
PMID: 30191401
Free PMC article.
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Synaptic pathology: A shared mechanism in neurological disease.
Henstridge CM, Pickett E, Spires-Jones TL.
Henstridge CM, et al.
Ageing Res Rev. 2016 Jul;28:72-84. doi: 10.1016/j.arr.2016.04.005. Epub 2016 Apr 20.
Ageing Res Rev. 2016.
PMID: 27108053
Free article.
Review.
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