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Lighting Up the Thrombin-Binding Aptamer G-Quadruplex with an Internal Cyanine-Indole-Quinolinium Nucleobase Surrogate. Direct Fluorescent Intensity Readout for Thrombin Binding without Topology Switching.
Bioconjug Chem. 2020 Nov 18;31(11):2596-2606. doi: 10.1021/acs.bioconjchem.0c00530. Epub 2020 Nov 6.
Bioconjug Chem. 2020.
PMID: 33156614
Manipulation of a DNA aptamer-protein binding site through arylation of internal guanine residues.
Van Riesen AJ, Fadock KL, Deore PS, Desoky A, Manderville RA, Sowlati-Hashjin S, Wetmore SD.
Van Riesen AJ, et al.
Org Biomol Chem. 2018 May 23;16(20):3831-3840. doi: 10.1039/c8ob00704g.
Org Biomol Chem. 2018.
PMID: 29745412
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Screening Internal Donor-Acceptor Biaryl Nucleobase Surrogates for Turn-On Fluorescence Affords an Aniline-Carboxythiophene Probe for Protein Detection by G-Quadruplex DNA.
Manning TW, Van Riesen AJ, Manderville RA.
Manning TW, et al. Among authors: van riesen aj.
Bioconjug Chem. 2021 Aug 18;32(8):1791-1801. doi: 10.1021/acs.bioconjchem.1c00270. Epub 2021 Jun 17.
Bioconjug Chem. 2021.
PMID: 34138558
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On-Strand Knoevenagel Insertion of a Hemicyanine Molecular Rotor Loop Residue for Turn-On Fluorescence Detection of Pb-Induced G-Quadruplex Rigidity.
Johnson RE, Van Riesen AJ, Manderville RA.
Johnson RE, et al. Among authors: van riesen aj.
Bioconjug Chem. 2021 Oct 20;32(10):2224-2232. doi: 10.1021/acs.bioconjchem.1c00386. Epub 2021 Sep 20.
Bioconjug Chem. 2021.
PMID: 34543022
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A Simple Molecular Rotor for Defining Nucleoside Environment within a DNA Aptamer-Protein Complex.
Cservenyi TZ, Van Riesen AJ, Berger FD, Desoky A, Manderville RA.
Cservenyi TZ, et al. Among authors: van riesen aj.
ACS Chem Biol. 2016 Sep 16;11(9):2576-82. doi: 10.1021/acschembio.6b00437. Epub 2016 Jul 27.
ACS Chem Biol. 2016.
PMID: 27447371
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Temperature Sensing of Thiolate Addition by Phenolate Merocyanine Dyes: Importance of the Quinone Methide Resonance Structure.
Van Riesen AJ, Johnson RE, Al-Abdul-Wahid MS, Liota C, Christyanton A, Manderville RA.
Van Riesen AJ, et al.
J Org Chem. 2021 Jan 15;86(2):1583-1590. doi: 10.1021/acs.joc.0c02428. Epub 2020 Dec 24.
J Org Chem. 2021.
PMID: 33356262
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Visible Fluorescent Light-up Probe for DNA Three-Way Junctions Provides Host-Guest Biosensing Applications.
Van Riesen AJ, Le J, Slavkovic S, Churcher ZR, Shoara AA, Johnson PE, Manderville RA.
Van Riesen AJ, et al.
ACS Appl Bio Mater. 2021 Sep 20;4(9):6732-6741. doi: 10.1021/acsabm.1c00431. Epub 2021 Aug 18.
ACS Appl Bio Mater. 2021.
PMID: 35006975
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