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Yes-associated protein (YAP) induces a secretome phenotype and transcriptionally regulates plasminogen activator Inhibitor-1 (PAI-1) expression in hepatocarcinogenesis.
Marquard S, Thomann S, Weiler SME, Bissinger M, Lutz T, Sticht C, Tóth M, de la Torre C, Gretz N, Straub BK, Marquardt J, Schirmacher P, Breuhahn K. Marquard S, et al. Among authors: marquardt j. Cell Commun Signal. 2020 Oct 23;18(1):166. doi: 10.1186/s12964-020-00634-6. Cell Commun Signal. 2020. PMID: 33097058 Free PMC article.
Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer.
Weiler SME, Pinna F, Wolf T, Lutz T, Geldiyev A, Sticht C, Knaub M, Thomann S, Bissinger M, Wan S, Rössler S, Becker D, Gretz N, Lang H, Bergmann F, Ustiyan V, Kalin TV, Singer S, Lee JS, Marquardt JU, Schirmacher P, Kalinichenko VV, Breuhahn K. Weiler SME, et al. Gastroenterology. 2017 Jun;152(8):2037-2051.e22. doi: 10.1053/j.gastro.2017.02.018. Epub 2017 Feb 27. Gastroenterology. 2017. PMID: 28249813
Cytoplasmic localization of the cell polarity factor scribble supports liver tumor formation and tumor cell invasiveness.
Wan S, Meyer AS, Weiler SME, Rupp C, Tóth M, Sticht C, Singer S, Thomann S, Roessler S, Schorpp-Kistner M, Schmitt J, Gretz N, Angel P, Tschaharganeh DF, Marquardt J, Schirmacher P, Pinna F, Breuhahn K. Wan S, et al. Among authors: marquardt j. Hepatology. 2018 May;67(5):1842-1856. doi: 10.1002/hep.29669. Epub 2018 Apr 1. Hepatology. 2018. PMID: 29152770
Loss of organic cation transporter 3 (Oct3) leads to enhanced proliferation and hepatocarcinogenesis.
Vollmar J, Lautem A, Closs E, Schuppan D, Kim YO, Grimm D, Marquardt JU, Fuchs P, Straub BK, Schad A, Gründemann D, Schattenberg JM, Gehrke N, Wörns MA, Baumgart J, Galle PR, Zimmermann T. Vollmar J, et al. Among authors: marquardt ju. Oncotarget. 2017 Dec 18;8(70):115667-115680. doi: 10.18632/oncotarget.23372. eCollection 2017 Dec 29. Oncotarget. 2017. PMID: 29383190 Free PMC article.
Application of patient-derived liver cancer cells for phenotypic characterization and therapeutic target identification.
Castven D, Becker D, Czauderna C, Wilhelm D, Andersen JB, Strand S, Hartmann M, Heilmann-Heimbach S, Roth W, Hartmann N, Straub BK, Mahn FL, Franck S, Pereira S, Haupts A, Vogel A, Wörns MA, Weinmann A, Heinrich S, Lang H, Thorgeirsson SS, Galle PR, Marquardt JU. Castven D, et al. Int J Cancer. 2019 Jun 1;144(11):2782-2794. doi: 10.1002/ijc.32026. Epub 2018 Dec 14. Int J Cancer. 2019. PMID: 30485423 Free article.
NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis.
Luiken S, Fraas A, Bieg M, Sugiyanto R, Goeppert B, Singer S, Ploeger C, Warsow G, Marquardt JU, Sticht C, De La Torre C, Pusch S, Mehrabi A, Gretz N, Schlesner M, Eils R, Schirmacher P, Longerich T, Roessler S. Luiken S, et al. Oncogene. 2020 Apr;39(15):3128-3144. doi: 10.1038/s41388-020-1198-3. Epub 2020 Feb 13. Oncogene. 2020. PMID: 32055024 Free PMC article.
329 results