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A compact beta model of huntingtin toxicity.
Zhang QC, Yeh TL, Leyva A, Frank LG, Miller J, Kim YE, Langen R, Finkbeiner S, Amzel ML, Ross CA, Poirier MA. Zhang QC, et al. Among authors: langen r. J Biol Chem. 2011 Mar 11;286(10):8188-8196. doi: 10.1074/jbc.M110.192013. Epub 2011 Jan 5. J Biol Chem. 2011. PMID: 21209075 Free PMC article.
Structural features and domain organization of huntingtin fibrils.
Bugg CW, Isas JM, Fischer T, Patterson PH, Langen R. Bugg CW, et al. Among authors: langen r. J Biol Chem. 2012 Sep 14;287(38):31739-46. doi: 10.1074/jbc.M112.353839. Epub 2012 Jul 16. J Biol Chem. 2012. PMID: 22801429 Free PMC article.
Rational design of potent domain antibody inhibitors of amyloid fibril assembly.
Ladiwala AR, Bhattacharya M, Perchiacca JM, Cao P, Raleigh DP, Abedini A, Schmidt AM, Varkey J, Langen R, Tessier PM. Ladiwala AR, et al. Among authors: langen r. Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):19965-70. doi: 10.1073/pnas.1208797109. Epub 2012 Nov 15. Proc Natl Acad Sci U S A. 2012. PMID: 23161913 Free PMC article.
Polyglutamine- and temperature-dependent conformational rigidity in mutant huntingtin revealed by immunoassays and circular dichroism spectroscopy.
Fodale V, Kegulian NC, Verani M, Cariulo C, Azzollini L, Petricca L, Daldin M, Boggio R, Padova A, Kuhn R, Pacifici R, Macdonald D, Schoenfeld RC, Park H, Isas JM, Langen R, Weiss A, Caricasole A. Fodale V, et al. Among authors: langen r. PLoS One. 2014 Dec 2;9(12):e112262. doi: 10.1371/journal.pone.0112262. eCollection 2014. PLoS One. 2014. PMID: 25464275 Free PMC article.
232 results