Vitale RM - Search Results

1

Design, Synthesis and In Vitro Experimental Validation of Novel TRPV4 Antagonists Inspired by Labdane Diterpenes.

Mazzotta S, Carullo G, Schiano Moriello A, Amodeo P, Di Marzo V, Vega-Holm M, Vitale RM, Aiello F, Brizzi A, De Petrocellis L. Mazzotta S, et al. Among authors: vitale rm. Mar Drugs. 2020 Oct 18;18(10):519. doi: 10.3390/md18100519. Mar Drugs. 2020. PMID: 33081023 Free PMC article.

2

Structure and absolute stereochemistry of syphonoside, a unique macrocyclic glycoterpenoid from marine organisms.

Gavagnin M, Carbone M, Amodeo P, Mollo E, Vitale RM, Roussis V, Cimino G. Gavagnin M, et al. Among authors: vitale rm. J Org Chem. 2007 Jul 20;72(15):5625-30. doi: 10.1021/jo0704917. Epub 2007 Jun 20. J Org Chem. 2007. PMID: 17580901

3

Structural analysis of BldR from Sulfolobus solfataricus provides insights into the molecular basis of transcriptional activation in Archaea by MarR family proteins.

Di Fiore A, Fiorentino G, Vitale RM, Ronca R, Amodeo P, Pedone C, Bartolucci S, De Simone G. Di Fiore A, et al. Among authors: vitale rm. J Mol Biol. 2009 May 8;388(3):559-69. doi: 10.1016/j.jmb.2009.03.030. Epub 2009 Mar 17. J Mol Biol. 2009. PMID: 19298823

4

A SPR strategy for high-throughput ligand screenings based on synthetic peptides mimicking a selected subdomain of the target protein: a proof of concept on HER2 receptor.

Monfregola L, Vitale RM, Amodeo P, De Luca S. Monfregola L, et al. Among authors: vitale rm. Bioorg Med Chem. 2009 Oct 1;17(19):7015-20. doi: 10.1016/j.bmc.2009.08.004. Epub 2009 Aug 8. Bioorg Med Chem. 2009. PMID: 19733086

5

Converting the highly amyloidogenic human calcitonin into a powerful fibril inhibitor by three-dimensional structure homology with a non-amyloidogenic analogue.

Andreotti G, Vitale RM, Avidan-Shpalter C, Amodeo P, Gazit E, Motta A. Andreotti G, et al. Among authors: vitale rm. J Biol Chem. 2011 Jan 28;286(4):2707-18. doi: 10.1074/jbc.M110.182014. Epub 2010 Nov 15. J Biol Chem. 2011. PMID: 21078667 Free PMC article.

6

Minimalist hybrid ligand/receptor-based pharmacophore model for CXCR4 applied to a small-library of marine natural products led to the identification of phidianidine a as a new CXCR4 ligand exhibiting antagonist activity.

Vitale RM, Gatti M, Carbone M, Barbieri F, Felicità V, Gavagnin M, Florio T, Amodeo P. Vitale RM, et al. ACS Chem Biol. 2013 Dec 20;8(12):2762-70. doi: 10.1021/cb400521b. Epub 2013 Oct 30. ACS Chem Biol. 2013. PMID: 24102412

7

Structure-activity relationships and molecular modelling of new 5-arylidene-4-thiazolidinone derivatives as aldose reductase inhibitors and potential anti-inflammatory agents.

Maccari R, Vitale RM, Ottanà R, Rocchiccioli M, Marrazzo A, Cardile V, Graziano AC, Amodeo P, Mura U, Del Corso A. Maccari R, et al. Among authors: vitale rm. Eur J Med Chem. 2014 Jun 23;81:1-14. doi: 10.1016/j.ejmech.2014.05.003. Epub 2014 May 4. Eur J Med Chem. 2014. PMID: 24819954

8

Air oxidation method employed for the disulfide bond formation of natural and synthetic peptides.

Calce E, Vitale RM, Scaloni A, Amodeo P, De Luca S. Calce E, et al. Among authors: vitale rm. Amino Acids. 2015 Aug;47(8):1507-15. doi: 10.1007/s00726-015-1983-4. Epub 2015 Apr 22. Amino Acids. 2015. PMID: 25900810

9

Interactions of GFAP with ceftriaxone and phenytoin: SRCD and molecular docking and dynamic simulation.

Ruzza P, Vitale RM, Hussain R, Biondi B, Amodeo P, Sechi G, Siligardi G. Ruzza P, et al. Among authors: vitale rm. Biochim Biophys Acta. 2016 Oct;1860(10):2239-48. doi: 10.1016/j.bbagen.2016.04.021. Epub 2016 Apr 28. Biochim Biophys Acta. 2016. PMID: 27133445 Free article.

10

Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents.

De Petrocellis L, Arroyo FJ, Orlando P, Schiano Moriello A, Vitale RM, Amodeo P, Sánchez A, Roncero C, Bianchini G, Martín MA, López-Alvarado P, Menéndez JC. De Petrocellis L, et al. Among authors: vitale rm. J Med Chem. 2016 Jun 23;59(12):5661-83. doi: 10.1021/acs.jmedchem.5b01448. Epub 2016 Jun 14. J Med Chem. 2016. PMID: 27232526

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