Rauch I - Search Results

1

NAIP-NLRC4-deficient mice are susceptible to shigellosis.

Mitchell PS, Roncaioli JL, Turcotte EA, Goers L, Chavez RA, Lee AY, Lesser CF, Rauch I, Vance RE. Mitchell PS, et al. Among authors: rauch i. Elife. 2020 Oct 19;9:e59022. doi: 10.7554/eLife.59022. Elife. 2020. PMID: 33074100 Free PMC article.

2

NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo.

Rauch I, Tenthorey JL, Nichols RD, Al Moussawi K, Kang JJ, Kang C, Kazmierczak BI, Vance RE. Rauch I, et al. J Exp Med. 2016 May 2;213(5):657-65. doi: 10.1084/jem.20151809. Epub 2016 Apr 4. J Exp Med. 2016. PMID: 27045008 Free PMC article.

3

NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8.

Rauch I, Deets KA, Ji DX, von Moltke J, Tenthorey JL, Lee AY, Philip NH, Ayres JS, Brodsky IE, Gronert K, Vance RE. Rauch I, et al. Immunity. 2017 Apr 18;46(4):649-659. doi: 10.1016/j.immuni.2017.03.016. Epub 2017 Apr 11. Immunity. 2017. PMID: 28410991 Free PMC article.

4

Gasdermin-D and Caspase-7 are the key Caspase-1/8 substrates downstream of the NAIP5/NLRC4 inflammasome required for restriction of Legionella pneumophila.

Gonçalves AV, Margolis SR, Quirino GFS, Mascarenhas DPA, Rauch I, Nichols RD, Ansaldo E, Fontana MF, Vance RE, Zamboni DS. Gonçalves AV, et al. Among authors: rauch i. PLoS Pathog. 2019 Jun 28;15(6):e1007886. doi: 10.1371/journal.ppat.1007886. eCollection 2019 Jun. PLoS Pathog. 2019. PMID: 31251782 Free PMC article.

5

NLRC4 inflammasome activation is NLRP3- and phosphorylation-independent during infection and does not protect from melanoma.

Tenthorey JL, Chavez RA, Thompson TW, Deets KA, Vance RE, Rauch I. Tenthorey JL, et al. Among authors: rauch i. J Exp Med. 2020 Jul 6;217(7):e20191736. doi: 10.1084/jem.20191736. J Exp Med. 2020. PMID: 32342103 Free PMC article.

6

The NAIP/NLRC4 inflammasome in infection and pathology.

Bauer R, Rauch I. Bauer R, et al. Among authors: rauch i. Mol Aspects Med. 2020 Dec;76:100863. doi: 10.1016/j.mam.2020.100863. Epub 2020 Jun 1. Mol Aspects Med. 2020. PMID: 32499055 Review.

7

Lytic Cell Death in Specific Microglial Subsets Is Required for Preventing Atypical Behavior in Mice.

Chuang HC, Nichols EK, Rauch I, Chang WC, Lin PM, Misra R, Kitaoka M, Vance RE, Saijo K. Chuang HC, et al. Among authors: rauch i. eNeuro. 2021 Jan 28;8(1):ENEURO.0342-20.2020. doi: 10.1523/ENEURO.0342-20.2020. Print 2021 Jan-Feb. eNeuro. 2021. PMID: 33414187 Free PMC article.

8

Epithelial Pyroptosis in Host Defense.

Churchill MJ, Mitchell PS, Rauch I. Churchill MJ, et al. Among authors: rauch i. J Mol Biol. 2022 Feb 28;434(4):167278. doi: 10.1016/j.jmb.2021.167278. Epub 2021 Oct 8. J Mol Biol. 2022. PMID: 34627788 Free PMC article. Review.

9

Inflammasome activation leads to cDC1-independent cross-priming of CD8 T cells by epithelial cell-derived antigen.

Deets KA, Nichols Doyle R, Rauch I, Vance RE. Deets KA, et al. Among authors: rauch i. Elife. 2021 Dec 23;10:e72082. doi: 10.7554/eLife.72082. Elife. 2021. PMID: 34939932 Free PMC article.

10

Human NAIP/NLRC4 and NLRP3 inflammasomes detect Salmonella type III secretion system activities to restrict intracellular bacterial replication.

Naseer N, Egan MS, Reyes Ruiz VM, Scott WP, Hunter EN, Demissie T, Rauch I, Brodsky IE, Shin S. Naseer N, et al. Among authors: rauch i. PLoS Pathog. 2022 Jan 24;18(1):e1009718. doi: 10.1371/journal.ppat.1009718. eCollection 2022 Jan. PLoS Pathog. 2022. PMID: 35073381 Free PMC article.

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