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Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer.
Morotti M, Zois CE, El-Ansari R, Craze ML, Rakha EA, Fan SJ, Valli A, Haider S, Goberdhan DCI, Green AR, Harris AL. Morotti M, et al. Among authors: valli a. Br J Cancer. 2021 Jan;124(2):494-505. doi: 10.1038/s41416-020-01113-y. Epub 2020 Oct 8. Br J Cancer. 2021. PMID: 33028955 Free PMC article.
Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer.
Morotti M, Bridges E, Valli A, Choudhry H, Sheldon H, Wigfield S, Gray N, Zois CE, Grimm F, Jones D, Teoh EJ, Cheng WC, Lord S, Anastasiou D, Haider S, McIntyre A, Goberdhan DCI, Buffa F, Harris AL. Morotti M, et al. Among authors: valli a. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12452-12461. doi: 10.1073/pnas.1818521116. Epub 2019 May 31. Proc Natl Acad Sci U S A. 2019. PMID: 31152137 Free PMC article.
Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism.
Valli A, Morotti M, Zois CE, Albers PK, Soga T, Feldinger K, Fischer R, Frejno M, McIntyre A, Bridges E, Haider S, Buffa FM, Baban D, Rodriguez M, Yanes O, Whittington HJ, Lake HA, Zervou S, Lygate CA, Kessler BM, Harris AL. Valli A, et al. Mol Cancer Res. 2019 Jul;17(7):1531-1544. doi: 10.1158/1541-7786.MCR-18-0315. Epub 2019 Mar 18. Mol Cancer Res. 2019. PMID: 30885992
Hypoxia metabolism in ageing.
Valli A, Harris AL, Kessler BM. Valli A, et al. Aging (Albany NY). 2015 Jul;7(7):465-6. doi: 10.18632/aging.100782. Aging (Albany NY). 2015. PMID: 26187134 Free PMC article. No abstract available.
The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells.
Leithner K, Triebl A, Trötzmüller M, Hinteregger B, Leko P, Wieser BI, Grasmann G, Bertsch AL, Züllig T, Stacher E, Valli A, Prassl R, Olschewski A, Harris AL, Köfeler HC, Olschewski H, Hrzenjak A. Leithner K, et al. Among authors: valli a. Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6225-6230. doi: 10.1073/pnas.1719871115. Epub 2018 May 29. Proc Natl Acad Sci U S A. 2018. PMID: 29844165 Free PMC article.
177 results