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Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer.
Morotti M, Zois CE, El-Ansari R, Craze ML, Rakha EA, Fan SJ, Valli A, Haider S, Goberdhan DCI, Green AR, Harris AL. Morotti M, et al. Among authors: goberdhan dci. Br J Cancer. 2021 Jan;124(2):494-505. doi: 10.1038/s41416-020-01113-y. Epub 2020 Oct 8. Br J Cancer. 2021. PMID: 33028955 Free PMC article.
PATs and SNATs: Amino Acid Sensors in Disguise.
Fan SJ, Goberdhan DCI. Fan SJ, et al. Among authors: goberdhan dci. Front Pharmacol. 2018 Jun 19;9:640. doi: 10.3389/fphar.2018.00640. eCollection 2018. Front Pharmacol. 2018. PMID: 29971004 Free PMC article.
Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer.
Morotti M, Bridges E, Valli A, Choudhry H, Sheldon H, Wigfield S, Gray N, Zois CE, Grimm F, Jones D, Teoh EJ, Cheng WC, Lord S, Anastasiou D, Haider S, McIntyre A, Goberdhan DCI, Buffa F, Harris AL. Morotti M, et al. Among authors: goberdhan dci. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12452-12461. doi: 10.1073/pnas.1818521116. Epub 2019 May 31. Proc Natl Acad Sci U S A. 2019. PMID: 31152137 Free PMC article.
Glutamine deprivation alters the origin and function of cancer cell exosomes.
Fan SJ, Kroeger B, Marie PP, Bridges EM, Mason JD, McCormick K, Zois CE, Sheldon H, Khalid Alham N, Johnson E, Ellis M, Stefana MI, Mendes CC, Wainwright SM, Cunningham C, Hamdy FC, Morris JF, Harris AL, Wilson C, Goberdhan DC. Fan SJ, et al. EMBO J. 2020 Aug 17;39(16):e103009. doi: 10.15252/embj.2019103009. Epub 2020 Jul 28. EMBO J. 2020. PMID: 32720716 Free PMC article.
Drosophila Sex Peptide controls the assembly of lipid microcarriers in seminal fluid.
Wainwright SM, Hopkins BR, Mendes CC, Sekar A, Kroeger B, Hellberg JEEU, Fan SJ, Pavey A, Marie PP, Leiblich A, Sepil I, Charles PD, Thézénas ML, Fischer R, Kessler BM, Gandy C, Corrigan L, Patel R, Wigby S, Morris JF, Goberdhan DCI, Wilson C. Wainwright SM, et al. Among authors: goberdhan dci. Proc Natl Acad Sci U S A. 2021 Feb 2;118(5):e2019622118. doi: 10.1073/pnas.2019622118. Proc Natl Acad Sci U S A. 2021. PMID: 33495334 Free PMC article.
44 results