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FAK activity in cancer-associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer.
Zaghdoudi S, Decaup E, Belhabib I, Samain R, Cassant-Sourdy S, Rochotte J, Brunel A, Schlaepfer D, Cros J, Neuzillet C, Strehaiano M, Alard A, Tomasini R, Rajeeve V, Perraud A, Mathonnet M, Pearce OM, Martineau Y, Pyronnet S, Bousquet C, Jean C. Zaghdoudi S, et al. Among authors: bousquet c. EMBO Mol Med. 2020 Nov 6;12(11):e12010. doi: 10.15252/emmm.202012010. Epub 2020 Oct 7. EMBO Mol Med. 2020. PMID: 33025708 Free PMC article.
Molecular signaling of somatostatin receptors.
Lahlou H, Guillermet J, Hortala M, Vernejoul F, Pyronnet S, Bousquet C, Susini C. Lahlou H, et al. Among authors: bousquet c. Ann N Y Acad Sci. 2004 Apr;1014:121-31. doi: 10.1196/annals.1294.012. Ann N Y Acad Sci. 2004. PMID: 15153426 Review.
Antitumor effects of somatostatin.
Pyronnet S, Bousquet C, Najib S, Azar R, Laklai H, Susini C. Pyronnet S, et al. Among authors: bousquet c. Mol Cell Endocrinol. 2008 May 14;286(1-2):230-7. doi: 10.1016/j.mce.2008.02.002. Epub 2008 Feb 13. Mol Cell Endocrinol. 2008. PMID: 18359151 Review.
Thrombospondin-1 is a critical effector of oncosuppressive activity of sst2 somatostatin receptor on pancreatic cancer.
Laklai H, Laval S, Dumartin L, Rochaix P, Hagedorn M, Bikfalvi A, Le Guellec S, Delisle MB, Schally AV, Susini C, Pyronnet S, Bousquet C. Laklai H, et al. Among authors: bousquet c. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17769-74. doi: 10.1073/pnas.0908674106. Epub 2009 Oct 1. Proc Natl Acad Sci U S A. 2009. PMID: 19805200 Free PMC article.
Control of contact-inhibition by 4E-BP1 upregulation.
Azar R, Susini C, Bousquet C, Pyronnet S. Azar R, et al. Among authors: bousquet c. Cell Cycle. 2010 Apr 1;9(7):1241-5. doi: 10.4161/cc.9.7.11047. Cell Cycle. 2010. PMID: 20372058
A switch of G protein-coupled receptor binding preference from phosphoinositide 3-kinase (PI3K)-p85 to filamin A negatively controls the PI3K pathway.
Najib S, Saint-Laurent N, Estève JP, Schulz S, Boutet-Robinet E, Fourmy D, Lättig J, Mollereau C, Pyronnet S, Susini C, Bousquet C. Najib S, et al. Among authors: bousquet c. Mol Cell Biol. 2012 Mar;32(5):1004-16. doi: 10.1128/MCB.06252-11. Epub 2011 Dec 27. Mol Cell Biol. 2012. PMID: 22203038 Free PMC article.
282 results