Foster RS - Search Results

1

The importance of expert review to clarify ambiguous situations for (Q)SAR predictions under ICH M7.

Foster RS, Fowkes A, Cayley A, Thresher A, Werner AD, Barber CG, Kocks G, Tennant RE, Williams RV, Kane S, Stalford SA. Foster RS, et al. Genes Environ. 2020 Sep 22;42:27. doi: 10.1186/s41021-020-00166-y. eCollection 2020. Genes Environ. 2020. PMID: 32983286 Free PMC article.

2

Are all nitrosamines concerning? A review of mutagenicity and carcinogenicity data.

Thresher A, Foster R, Ponting DJ, Stalford SA, Tennant RE, Thomas R. Thresher A, et al. Regul Toxicol Pharmacol. 2020 Oct;116:104749. doi: 10.1016/j.yrtph.2020.104749. Epub 2020 Aug 7. Regul Toxicol Pharmacol. 2020. PMID: 32777431 Review.

3

Beyond adverse outcome pathways: making toxicity predictions from event networks, SAR models, data and knowledge.

Ball T, Barber CG, Cayley A, Chilton ML, Foster R, Fowkes A, Heghes C, Hill E, Hill N, Kane S, Macmillan DS, Myden A, Newman D, Polit A, Stalford SA, Vessey JD. Ball T, et al. Toxicol Res (Camb). 2021 Jan 22;10(1):102-122. doi: 10.1093/toxres/tfaa099. eCollection 2021 Jan. Toxicol Res (Camb). 2021. PMID: 33613978 Free PMC article.

4

Use of Lhasa Limited Products for the In Silico Prediction of Drug Toxicity.

Ponting DJ, Burns MJ, Foster RS, Hemingway R, Kocks G, MacMillan DS, Shannon-Little AL, Tennant RE, Tidmarsh JR, Yeo DJ. Ponting DJ, et al. Among authors: foster rs. Methods Mol Biol. 2022;2425:435-478. doi: 10.1007/978-1-0716-1960-5_17. Methods Mol Biol. 2022. PMID: 35188642

5

Development of a network of carcinogenicity adverse outcome pathways and its employment as an evidence framework for safety assessment.

Cayley AN, Foster RS, Hill E, Kane S, Kocks G, Myden A, Newman D, Stalford SA, Vessey JD, Zarei R, De Oliveira AAF. Cayley AN, et al. Among authors: foster rs. ALTEX. 2023;40(1):34–52. doi: 10.14573/altex.2201311. Epub 2022 May 13. ALTEX. 2023. PMID: 35575642 Free article.

6

Updating the Dermal Sensitisation Thresholds using an expanded dataset and an in silico expert system.

Chilton ML, Api AM, Foster RS, Gerberick GF, Lavelle M, Macmillan DS, Na M, O'Brien D, O'Leary-Steele C, Patel M, Ponting DJ, Roberts DW, Safford RJ, Tennant RE. Chilton ML, et al. Among authors: foster rs. Regul Toxicol Pharmacol. 2022 Aug;133:105200. doi: 10.1016/j.yrtph.2022.105200. Epub 2022 Jun 1. Regul Toxicol Pharmacol. 2022. PMID: 35662638 Free article.

7

Enhancing global and local decision making for chemical safety assessments through increasing the availability of data.

Fowkes A, Foster R, Kane S, Thresher A, Werner AL, de Oliveira AAF. Fowkes A, et al. Toxicol Mech Methods. 2023 Jun;33(5):337-348. doi: 10.1080/15376516.2022.2156007. Epub 2023 Jan 4. Toxicol Mech Methods. 2023. PMID: 36600456 Review.

8

Assessing the utility of common arguments used in expert review of in silico predictions as part of ICH M7 assessments.

Cayley AN, Foster RS, Brigo A, Muster W, Musso A, Kenyon MO, Parris P, White AT, Cohen-Ohana M, Nudelman R, Glowienke S. Cayley AN, et al. Among authors: foster rs. Regul Toxicol Pharmacol. 2023 Oct;144:105490. doi: 10.1016/j.yrtph.2023.105490. Epub 2023 Aug 31. Regul Toxicol Pharmacol. 2023. PMID: 37659712

9

Revisiting the Landscape of Potential Small and Drug Substance Related Nitrosamines in Pharmaceuticals.

Burns MJ, Ponting DJ, Foster RS, Thornton BP, Romero NE, Smith GF, Ashworth IW, Teasdale A, Simon S, Schlingemann J. Burns MJ, et al. Among authors: foster rs. J Pharm Sci. 2023 Dec;112(12):3005-3011. doi: 10.1016/j.xphs.2023.10.001. Epub 2023 Oct 5. J Pharm Sci. 2023. PMID: 37805074 Free article.

10

Evaluation of QSAR models for predicting mutagenicity: outcome of the Second Ames/QSAR international challenge project.

Furuhama A, Kitazawa A, Yao J, Matos Dos Santos CE, Rathman J, Yang C, Ribeiro JV, Cross K, Myatt G, Raitano G, Benfenati E, Jeliazkova N, Saiakhov R, Chakravarti S, Foster RS, Bossa C, Battistelli CL, Benigni R, Sawada T, Wasada H, Hashimoto T, Wu M, Barzilay R, Daga PR, Clark RD, Mestres J, Montero A, Gregori-Puigjané E, Petkov P, Ivanova H, Mekenyan O, Matthews S, Guan D, Spicer J, Lui R, Uesawa Y, Kurosaki K, Matsuzaka Y, Sasaki S, Cronin MTD, Belfield SJ, Firman JW, Spînu N, Qiu M, Keca JM, Gini G, Li T, Tong W, Hong H, Liu Z, Igarashi Y, Yamada H, Sugiyama KI, Honma M. Furuhama A, et al. Among authors: foster rs. SAR QSAR Environ Res. 2023 Oct-Dec;34(12):983-1001. doi: 10.1080/1062936X.2023.2284902. Epub 2023 Dec 4. SAR QSAR Environ Res. 2023. PMID: 38047445

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