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Molecular determinants of enhanced response to somatostatin receptor ligands after debulking in large GH-producing adenomas.
Gil J, Marques-Pamies M, Jordà M, Fajardo-Montañana C, García-Martínez A, Sampedro M, Serra G, Salinas I, Blanco A, Valassi E, Sesmilo G, Carrato C, Cámara R, Lamas C, Casano-Sancho P, Alvarez CV, Bernabéu I, Webb SM, Picó A, Marazuela M, Puig-Domingo M; on behalf REMAH investigators. Gil J, et al. Among authors: alvarez cv. Clin Endocrinol (Oxf). 2021 May;94(5):811-819. doi: 10.1111/cen.14339. Epub 2021 Mar 14. Clin Endocrinol (Oxf). 2021. PMID: 32978826
Humanized medium (h7H) allows long-term primary follicular thyroid cultures from human normal thyroid, benign neoplasm, and cancer.
Bravo SB, Garcia-Rendueles ME, Garcia-Rendueles AR, Rodrigues JS, Perez-Romero S, Garcia-Lavandeira M, Suarez-Fariña M, Barreiro F, Czarnocka B, Senra A, Lareu MV, Rodriguez-Garcia J, Cameselle-Teijeiro J, Alvarez CV. Bravo SB, et al. Among authors: alvarez cv. J Clin Endocrinol Metab. 2013 Jun;98(6):2431-41. doi: 10.1210/jc.2012-3812. Epub 2013 Mar 28. J Clin Endocrinol Metab. 2013. PMID: 23539720
Somatotropinomas, but not nonfunctioning pituitary adenomas, maintain a functional apoptotic RET/Pit1/ARF/p53 pathway that is blocked by excess GDNF.
Diaz-Rodriguez E, Garcia-Rendueles AR, Ibáñez-Costa A, Gutierrez-Pascual E, Garcia-Lavandeira M, Leal A, Japon MA, Soto A, Venegas E, Tinahones FJ, Garcia-Arnes JA, Benito P, Angeles Galvez M, Jimenez-Reina L, Bernabeu I, Dieguez C, Luque RM, Castaño JP, Alvarez CV. Diaz-Rodriguez E, et al. Among authors: alvarez cv. Endocrinology. 2014 Nov;155(11):4329-40. doi: 10.1210/en.2014-1034. Epub 2014 Aug 19. Endocrinology. 2014. PMID: 25137025
The Molecular Registry of Pituitary Adenomas (REMAH): A bet of Spanish Endocrinology for the future of individualized medicine and translational research.
Luque RM, Ibáñez-Costa A, Sánchez-Tejada L, Rivero-Cortés E, Robledo M, Madrazo-Atutxa A, Mora M, Álvarez CV, Lucas-Morante T, Álvarez-Escolá C, Fajardo C, Castaño L, Gaztambide S, Venegas-Moreno E, Soto-Moreno A, Gálvez MÁ, Salvador J, Valassi E, Webb SM, Picó A, Puig-Domingo M, Gilabert M, Bernabéu I, Marazuela M, Leal-Cerro A, Castaño JP; investigadores del REMAH. Luque RM, et al. Among authors: alvarez cv, alvarez escola c. Endocrinol Nutr. 2016 Jun-Jul;63(6):274-84. doi: 10.1016/j.endonu.2016.03.001. Epub 2016 Apr 16. Endocrinol Nutr. 2016. PMID: 27091627 English, Spanish.
Unmasking a new prognostic marker and therapeutic target from the GDNF-RET/PIT1/p14ARF/p53 pathway in acromegaly.
Chenlo M, Rodriguez-Gomez IA, Serramito R, Garcia-Rendueles AR, Villar-Taibo R, Fernandez-Rodriguez E, Perez-Romero S, Suarez-Fariña M, Garcia-Allut A, Cabezas-Agricola JM, Rodriguez-Garcia J, Lear PV, Alvarez-San Martin RM, Alvarez-Escola C, Bernabeu I, Alvarez CV. Chenlo M, et al. Among authors: alvarez cv, alvarez san martin rm, alvarez escola c. EBioMedicine. 2019 May;43:537-552. doi: 10.1016/j.ebiom.2019.04.007. Epub 2019 Apr 8. EBioMedicine. 2019. PMID: 30975543 Free PMC article.
Molecular profiling for acromegaly treatment: a validation study.
Puig-Domingo M, Gil J, Sampedro-Nuñez M, Jordà M, Webb SM, Serra G, Pons L, Salinas I, Blanco A, Marques-Pamies M, Valassi E, Picó A, García-Martínez A, Carrato C, Buj R, Del Pozo C, Obiols G, Villabona C, Cámara R, Fajardo-Montañana C, Alvarez CV, Bernabéu I, Marazuela M. Puig-Domingo M, et al. Among authors: alvarez cv. Endocr Relat Cancer. 2020 Jun;27(6):375-389. doi: 10.1530/ERC-18-0565. Endocr Relat Cancer. 2020. PMID: 32302973
81 results