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Distinct phosphorylation sites in a prototypical GPCR differently orchestrate β-arrestin interaction, trafficking, and signaling.
Dwivedi-Agnihotri H, Chaturvedi M, Baidya M, Stepniewski TM, Pandey S, Maharana J, Srivastava A, Caengprasath N, Hanyaloglu AC, Selent J, Shukla AK. Dwivedi-Agnihotri H, et al. Among authors: shukla ak. Sci Adv. 2020 Sep 11;6(37):eabb8368. doi: 10.1126/sciadv.abb8368. Print 2020 Sep. Sci Adv. 2020. PMID: 32917711 Free PMC article.
Functional competence of a partially engaged GPCR-β-arrestin complex.
Kumari P, Srivastava A, Banerjee R, Ghosh E, Gupta P, Ranjan R, Chen X, Gupta B, Gupta C, Jaiman D, Shukla AK. Kumari P, et al. Among authors: shukla ak. Nat Commun. 2016 Nov 9;7:13416. doi: 10.1038/ncomms13416. Nat Commun. 2016. PMID: 27827372 Free PMC article.
Biased Opioid Receptor Ligands: Gain without Pain.
Ranjan R, Pandey S, Shukla AK. Ranjan R, et al. Among authors: shukla ak. Trends Endocrinol Metab. 2017 Apr;28(4):247-249. doi: 10.1016/j.tem.2017.01.001. Epub 2017 Jan 16. Trends Endocrinol Metab. 2017. PMID: 28110810 Review.
A synthetic intrabody-based selective and generic inhibitor of GPCR endocytosis.
Ghosh E, Srivastava A, Baidya M, Kumari P, Dwivedi H, Nidhi K, Ranjan R, Dogra S, Koide A, Yadav PN, Sidhu SS, Koide S, Shukla AK. Ghosh E, et al. Among authors: shukla ak. Nat Nanotechnol. 2017 Dec;12(12):1190-1198. doi: 10.1038/nnano.2017.188. Epub 2017 Oct 2. Nat Nanotechnol. 2017. PMID: 28967893 Free PMC article.
GPCR Signaling: The Interplay of Gαi and β-arrestin.
Dwivedi H, Baidya M, Shukla AK. Dwivedi H, et al. Among authors: shukla ak. Curr Biol. 2018 Apr 2;28(7):R324-R327. doi: 10.1016/j.cub.2018.02.027. Curr Biol. 2018. PMID: 29614294 Free article.
534 results