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Page 1
Fibrosis and Immune Cell Infiltration Are Separate Events Regulated by Cell-Specific Receptor Notch3 Expression.
Brandt S, Ballhause TM, Bernhardt A, Becker A, Salaru D, Le-Deffge HM, Fehr A, Fu Y, Philipsen L, Djudjaj S, Müller AJ, Kramann R, Ibrahim M, Geffers R, Siebel C, Isermann B, Heidel FH, Lindquist JA, Mertens PR. Brandt S, et al. Among authors: kramann r. J Am Soc Nephrol. 2020 Nov;31(11):2589-2608. doi: 10.1681/ASN.2019121289. Epub 2020 Aug 28. J Am Soc Nephrol. 2020. PMID: 32859670 Free PMC article.
A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology.
Petersen J, Englmaier L, Artemov AV, Poverennaya I, Mahmoud R, Bouderlique T, Tesarova M, Deviatiiarov R, Szilvásy-Szabó A, Akkuratov EE, Pajuelo Reguera D, Zeberg H, Kaucka M, Kastriti ME, Krivanek J, Radaszkiewicz T, Gömöryová K, Knauth S, Potesil D, Zdrahal Z, Ganji RS, Grabowski A, Buhl ME, Zikmund T, Kavkova M, Axelson H, Lindgren D, Kramann R, Kuppe C, Erdélyi F, Máté Z, Szabó G, Koehne T, Harkany T, Fried K, Kaiser J, Boor P, Fekete C, Rozman J, Kasparek P, Prochazka J, Sedlacek R, Bryja V, Gusev O, Adameyko I. Petersen J, et al. Among authors: kramann r. Nat Commun. 2023 May 29;14(1):3092. doi: 10.1038/s41467-023-38663-7. Nat Commun. 2023. PMID: 37248239 Free PMC article.
Elastin imaging enables noninvasive staging and treatment monitoring of kidney fibrosis.
Sun Q, Baues M, Klinkhammer BM, Ehling J, Djudjaj S, Drude NI, Daniel C, Amann K, Kramann R, Kim H, Saez-Rodriguez J, Weiskirchen R, Onthank DC, Botnar RM, Kiessling F, Floege J, Lammers T, Boor P. Sun Q, et al. Among authors: kramann r. Sci Transl Med. 2019 Apr 3;11(486):eaat4865. doi: 10.1126/scitranslmed.aat4865. Sci Transl Med. 2019. PMID: 30944168 Free PMC article.
Only Hyperuricemia with Crystalluria, but not Asymptomatic Hyperuricemia, Drives Progression of Chronic Kidney Disease.
Sellmayr M, Hernandez Petzsche MR, Ma Q, Krüger N, Liapis H, Brink A, Lenz B, Angelotti ML, Gnemmi V, Kuppe C, Kim H, Bindels EMJ, Tajti F, Saez-Rodriguez J, Lech M, Kramann R, Romagnani P, Anders HJ, Steiger S. Sellmayr M, et al. Among authors: kramann r. J Am Soc Nephrol. 2020 Dec;31(12):2773-2792. doi: 10.1681/ASN.2020040523. Epub 2020 Sep 16. J Am Soc Nephrol. 2020. PMID: 32938648 Free PMC article.
Deep Learning-Based Segmentation and Quantification in Experimental Kidney Histopathology.
Bouteldja N, Klinkhammer BM, Bülow RD, Droste P, Otten SW, Freifrau von Stillfried S, Moellmann J, Sheehan SM, Korstanje R, Menzel S, Bankhead P, Mietsch M, Drummer C, Lehrke M, Kramann R, Floege J, Boor P, Merhof D. Bouteldja N, et al. Among authors: kramann r. J Am Soc Nephrol. 2021 Jan;32(1):52-68. doi: 10.1681/ASN.2020050597. Epub 2020 Nov 5. J Am Soc Nephrol. 2021. PMID: 33154175 Free PMC article.
Decoding myofibroblast origins in human kidney fibrosis.
Kuppe C, Ibrahim MM, Kranz J, Zhang X, Ziegler S, Perales-Patón J, Jansen J, Reimer KC, Smith JR, Dobie R, Wilson-Kanamori JR, Halder M, Xu Y, Kabgani N, Kaesler N, Klaus M, Gernhold L, Puelles VG, Huber TB, Boor P, Menzel S, Hoogenboezem RM, Bindels EMJ, Steffens J, Floege J, Schneider RK, Saez-Rodriguez J, Henderson NC, Kramann R. Kuppe C, et al. Among authors: kramann r. Nature. 2021 Jan;589(7841):281-286. doi: 10.1038/s41586-020-2941-1. Epub 2020 Nov 11. Nature. 2021. PMID: 33176333 Free PMC article.
Mouse Models of Kidney Fibrosis.
Kramann R, Menzel S. Kramann R, et al. Methods Mol Biol. 2021;2299:323-338. doi: 10.1007/978-1-0716-1382-5_22. Methods Mol Biol. 2021. PMID: 34028752
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids.
Jansen J, Reimer KC, Nagai JS, Varghese FS, Overheul GJ, de Beer M, Roverts R, Daviran D, Fermin LAS, Willemsen B, Beukenboom M, Djudjaj S, von Stillfried S, van Eijk LE, Mastik M, Bulthuis M, Dunnen WD, van Goor H, Hillebrands JL, Triana SH, Alexandrov T, Timm MC, van den Berge BT, van den Broek M, Nlandu Q, Heijnert J, Bindels EMJ, Hoogenboezem RM, Mooren F, Kuppe C, Miesen P, Grünberg K, Ijzermans T, Steenbergen EJ, Czogalla J, Schreuder MF, Sommerdijk N, Akiva A, Boor P, Puelles VG, Floege J, Huber TB; COVID Moonshot consortium; van Rij RP, Costa IG, Schneider RK, Smeets B, Kramann R. Jansen J, et al. Among authors: kramann r. Cell Stem Cell. 2022 Feb 3;29(2):217-231.e8. doi: 10.1016/j.stem.2021.12.010. Epub 2021 Dec 25. Cell Stem Cell. 2022. PMID: 35032430 Free PMC article.
172 results