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First Human Use of RUC-4: A Nonactivating Second-Generation Small-Molecule Platelet Glycoprotein IIb/IIIa (Integrin αIIbβ3) Inhibitor Designed for Subcutaneous Point-of-Care Treatment of ST-Segment-Elevation Myocardial Infarction.
J Am Heart Assoc. 2020 Sep;9(17):e016552. doi: 10.1161/JAHA.120.016552. Epub 2020 Aug 26.
J Am Heart Assoc. 2020.
PMID: 32844723
Free PMC article.
Clinical Trial.
When Bioequivalence in Healthy Volunteers May not Translate to Bioequivalence in Patients: Differential Effects of Increased Gastric pH on the Pharmacokinetics of Levothyroxine Capsules and Tablets.
Seng Yue C, Benvenga S, Scarsi C, Loprete L, Ducharme MP.
Seng Yue C, et al.
J Pharm Pharm Sci. 2015;18(5):844-55. doi: 10.18433/j36p5m.
J Pharm Pharm Sci. 2015.
PMID: 26670370
Free article.
Item in Clipboard
A randomized, double-blind, placebo-controlled, single and multiple ascending dose Phase 1 study to determine the safety, pharmacokinetics and food and faecal microbiome effects of ibezapolstat administered orally to healthy subjects.
Garey KW, Begum K, Lancaster C, Gonzales-Luna A, Bui D, Mercier J, Seng Yue C, Ducharme MP, Hu M, Vince B, Silverman MH, Alam MJ, Kankam M.
Garey KW, et al. Among authors: seng yue c.
J Antimicrob Chemother. 2020 Dec 1;75(12):3635-3643. doi: 10.1093/jac/dkaa364.
J Antimicrob Chemother. 2020.
PMID: 32892222
Free PMC article.
Clinical Trial.
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Novel population pharmacokinetic method compared to the standard noncompartmental approach to assess bioequivalence of iron gluconate formulations.
Seng Yue C, Gallicano K, Labbé L, Ducharme MP.
Seng Yue C, et al.
J Pharm Pharm Sci. 2013;16(3):424-40. doi: 10.18433/j3hs42.
J Pharm Pharm Sci. 2013.
PMID: 24021291
Free article.
Clinical Trial.
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Opportunities and Challenges Related to the Implementation of Model-Based Bioequivalence Criteria.
Seng Yue C, Ozdin D, Selber-Hnatiw S, Ducharme MP.
Seng Yue C, et al.
Clin Pharmacol Ther. 2019 Feb;105(2):350-362. doi: 10.1002/cpt.1270. Epub 2019 Jan 8.
Clin Pharmacol Ther. 2019.
PMID: 30375647
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Proton Pump Inhibitors Do Not Affect the Bioavailability of a Novel Liquid Formulation of Levothyroxine.
Seng Yue C, Scarsi C, Bettazzi E, Mautone G, Celi FS, Ducharme M.
Seng Yue C, et al.
Endocr Pract. 2024 Mar 28:S1530-891X(24)00471-3. doi: 10.1016/j.eprac.2024.03.388. Online ahead of print.
Endocr Pract. 2024.
PMID: 38554774
Free article.
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