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Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.
Li X, Li Z, Zhou H, Gaynor SM, Liu Y, Chen H, Sun R, Dey R, Arnett DK, Aslibekyan S, Ballantyne CM, Bielak LF, Blangero J, Boerwinkle E, Bowden DW, Broome JG, Conomos MP, Correa A, Cupples LA, Curran JE, Freedman BI, Guo X, Hindy G, Irvin MR, Kardia SLR, Kathiresan S, Khan AT, Kooperberg CL, Laurie CC, Liu XS, Mahaney MC, Manichaikul AW, Martin LW, Mathias RA, McGarvey ST, Mitchell BD, Montasser ME, Moore JE, Morrison AC, O'Connell JR, Palmer ND, Pampana A, Peralta JM, Peyser PA, Psaty BM, Redline S, Rice KM, Rich SS, Smith JA, Tiwari HK, Tsai MY, Vasan RS, Wang FF, Weeks DE, Weng Z, Wilson JG, Yanek LR; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Lipids Working Group; Neale BM, Sunyaev SR, Abecasis GR, Rotter JI, Willer CJ, Peloso GM, Natarajan P, Lin X. Li X, et al. Among authors: mcgarvey st. Nat Genet. 2020 Sep;52(9):969-983. doi: 10.1038/s41588-020-0676-4. Epub 2020 Aug 24. Nat Genet. 2020. PMID: 32839606 Free PMC article.
Human leptin locus (LEP) alleles and BMI in Samoans.
McGarvey ST, Forrest W, Weeks DE, Sun G, Smelser D, Tufa J, Viali S, Deka R. McGarvey ST, et al. Int J Obes Relat Metab Disord. 2002 Jun;26(6):783-8. doi: 10.1038/sj.ijo.0801996. Int J Obes Relat Metab Disord. 2002. PMID: 12037648
Genome-wide scan for adiposity-related phenotypes in adults from American Samoa.
Dai F, Keighley ED, Sun G, Indugula SR, Roberts ST, Aberg K, Smelser D, Tuitele J, Jin L, Deka R, Weeks DE, McGarvey ST. Dai F, et al. Among authors: mcgarvey st. Int J Obes (Lond). 2007 Dec;31(12):1832-42. doi: 10.1038/sj.ijo.0803675. Epub 2007 Jul 10. Int J Obes (Lond). 2007. PMID: 17621312
INSIG2 variants, dietary patterns and metabolic risk in Samoa.
Baylin A, Deka R, Tuitele J, Viali S, Weeks DE, McGarvey ST. Baylin A, et al. Among authors: mcgarvey st. Eur J Clin Nutr. 2013 Jan;67(1):101-7. doi: 10.1038/ejcn.2012.124. Epub 2012 Sep 12. Eur J Clin Nutr. 2013. PMID: 22968099 Free PMC article.
275 results