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Structure guided design and synthesis of furyl thiazolidinedione derivatives as inhibitors of GLUT 1 and GLUT 4, and evaluation of their anti-leukemic potential.
Tilekar K, Upadhyay N, Hess JD, Macias LH, Mrowka P, Aguilera RJ, Meyer-Almes FJ, Iancu CV, Choe JY, Ramaa CS. Tilekar K, et al. Among authors: mrowka p. Eur J Med Chem. 2020 Sep 15;202:112603. doi: 10.1016/j.ejmech.2020.112603. Epub 2020 Jul 2. Eur J Med Chem. 2020. PMID: 32634629 Free PMC article.
Heme oxygenase-1 protects tumor cells against photodynamic therapy-mediated cytotoxicity.
Nowis D, Legat M, Grzela T, Niderla J, Wilczek E, Wilczynski GM, Głodkowska E, Mrówka P, Issat T, Dulak J, Józkowicz A, Waś H, Adamek M, Wrzosek A, Nazarewski S, Makowski M, Stokłosa T, Jakóbisiak M, Gołab J. Nowis D, et al. Among authors: mrowka p. Oncogene. 2006 Jun 8;25(24):3365-74. doi: 10.1038/sj.onc.1209378. Epub 2006 Feb 6. Oncogene. 2006. PMID: 16462769 Free PMC article.
Statins impair antitumor effects of rituximab by inducing conformational changes of CD20.
Winiarska M, Bil J, Wilczek E, Wilczynski GM, Lekka M, Engelberts PJ, Mackus WJ, Gorska E, Bojarski L, Stoklosa T, Nowis D, Kurzaj Z, Makowski M, Glodkowska E, Issat T, Mrowka P, Lasek W, Dabrowska-Iwanicka A, Basak GW, Wasik M, Warzocha K, Sinski M, Gaciong Z, Jakobisiak M, Parren PW, Golab J. Winiarska M, et al. Among authors: mrowka p. PLoS Med. 2008 Mar 25;5(3):e64. doi: 10.1371/journal.pmed.0050064. PLoS Med. 2008. PMID: 18366248 Free PMC article.
Proteasome inhibition potentiates antitumor effects of photodynamic therapy in mice through induction of endoplasmic reticulum stress and unfolded protein response.
Szokalska A, Makowski M, Nowis D, Wilczynski GM, Kujawa M, Wójcik C, Mlynarczuk-Bialy I, Salwa P, Bil J, Janowska S, Agostinis P, Verfaillie T, Bugajski M, Gietka J, Issat T, Glodkowska E, Mrówka P, Stoklosa T, Hamblin MR, Mróz P, Jakóbisiak M, Golab J. Szokalska A, et al. Among authors: mrowka p. Cancer Res. 2009 May 15;69(10):4235-43. doi: 10.1158/0008-5472.CAN-08-3439. Epub 2009 May 12. Cancer Res. 2009. PMID: 19435917 Free PMC article.
26 results