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Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution.
Yap YW, Rusu PM, Chan AY, Fam BC, Jungmann A, Solon-Biet SM, Barlow CK, Creek DJ, Huang C, Schittenhelm RB, Morgan B, Schmoll D, Kiens B, Piper MDW, Heikenwälder M, Simpson SJ, Bröer S, Andrikopoulos S, Müller OJ, Rose AJ. Yap YW, et al. Among authors: schmoll d. Nat Commun. 2020 Jun 9;11(1):2894. doi: 10.1038/s41467-020-16568-z. Nat Commun. 2020. PMID: 32518324 Free PMC article.
A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution.
Maida A, Zota A, Sjøberg KA, Schumacher J, Sijmonsma TP, Pfenninger A, Christensen MM, Gantert T, Fuhrmeister J, Rothermel U, Schmoll D, Heikenwälder M, Iovanna JL, Stemmer K, Kiens B, Herzig S, Rose AJ. Maida A, et al. Among authors: schmoll d. J Clin Invest. 2016 Sep 1;126(9):3263-78. doi: 10.1172/JCI85946. Epub 2016 Aug 22. J Clin Invest. 2016. PMID: 27548521 Free PMC article.
Short-term dietary reduction of branched-chain amino acids reduces meal-induced insulin secretion and modifies microbiome composition in type 2 diabetes: a randomized controlled crossover trial.
Karusheva Y, Koessler T, Strassburger K, Markgraf D, Mastrototaro L, Jelenik T, Simon MC, Pesta D, Zaharia OP, Bódis K, Bärenz F, Schmoll D, Wolkersdorfer M, Tura A, Pacini G, Burkart V, Müssig K, Szendroedi J, Roden M. Karusheva Y, et al. Among authors: schmoll d. Am J Clin Nutr. 2019 Nov 1;110(5):1098-1107. doi: 10.1093/ajcn/nqz191. Am J Clin Nutr. 2019. PMID: 31667519 Free PMC article. Clinical Trial.
Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase.
Nguyen-Tu MS, Harris J, Martinez-Sanchez A, Chabosseau P, Hu M, Georgiadou E, Pollard A, Otero P, Lopez-Noriega L, Leclerc I, Sakamoto K, Schmoll D, Smith DM, Carling D, Rutter GA. Nguyen-Tu MS, et al. Among authors: schmoll d. Diabetologia. 2022 Jun;65(6):997-1011. doi: 10.1007/s00125-022-05673-x. Epub 2022 Mar 16. Diabetologia. 2022. PMID: 35294578 Free PMC article.
Inhibition of citrate cotransporter Slc13a5/mINDY by RNAi improves hepatic insulin sensitivity and prevents diet-induced non-alcoholic fatty liver disease in mice.
Brachs S, Winkel AF, Tang H, Birkenfeld AL, Brunner B, Jahn-Hofmann K, Margerie D, Ruetten H, Schmoll D, Spranger J. Brachs S, et al. Among authors: schmoll d. Mol Metab. 2016 Aug 13;5(11):1072-1082. doi: 10.1016/j.molmet.2016.08.004. eCollection 2016 Nov. Mol Metab. 2016. PMID: 27818933 Free PMC article.
81 results