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Synthesis of SMT022357 enantiomers and in vivo evaluation in a Duchenne muscular dystrophy mouse model.
Tetrahedron. 2020 Jan 10;76(2):130819. doi: 10.1016/j.tet.2019.130819.
Tetrahedron. 2020.
PMID: 32713969
Free PMC article.
2-Arylbenzo[d]oxazole Phosphinate Esters as Second-Generation Modulators of Utrophin for the Treatment of Duchenne Muscular Dystrophy.
Babbs A, Berg A, Chatzopoulou M, Davies KE, Davies SG, Edwards B, Elsey DJ, Emer E, Guiraud S, Harriman S, Lecci C, Moir L, Peters D, Robinson N, Rowley JA, Russell AJ, Squire SE, Tinsley JM, Wilson FX, Wynne GM.
Babbs A, et al. Among authors: elsey dj.
J Med Chem. 2020 Jul 23;63(14):7880-7891. doi: 10.1021/acs.jmedchem.0c00807. Epub 2020 Jul 10.
J Med Chem. 2020.
PMID: 32551645
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Isolation, Structural Identification, Synthesis, and Pharmacological Profiling of 1,2-trans-Dihydro-1,2-diol Metabolites of the Utrophin Modulator Ezutromid.
Chatzopoulou M, Claridge TDW, Davies KE, Davies SG, Elsey DJ, Emer E, Fletcher AM, Harriman S, Robinson N, Rowley JA, Russell AJ, Tinsley JM, Weaver R, Wilkinson IVL, Willis NJ, Wilson FX, Wynne GM.
Chatzopoulou M, et al. Among authors: elsey dj.
J Med Chem. 2020 Mar 12;63(5):2547-2556. doi: 10.1021/acs.jmedchem.9b01547. Epub 2019 Oct 25.
J Med Chem. 2020.
PMID: 31599580
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Second-generation compound for the modulation of utrophin in the therapy of DMD.
Guiraud S, Squire SE, Edwards B, Chen H, Burns DT, Shah N, Babbs A, Davies SG, Wynne GM, Russell AJ, Elsey D, Wilson FX, Tinsley JM, Davies KE.
Guiraud S, et al.
Hum Mol Genet. 2015 Aug 1;24(15):4212-24. doi: 10.1093/hmg/ddv154. Epub 2015 May 1.
Hum Mol Genet. 2015.
PMID: 25935002
Free PMC article.
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"Of Mice and Measures": A Project to Improve How We Advance Duchenne Muscular Dystrophy Therapies to the Clinic.
Gordish-Dressman H, Willmann R, Dalle Pazze L, Kreibich A, van Putten M, Heydemann A, Bogdanik L, Lutz C, Davies K, Demonbreun AR, Duan D, Elsey D, Fukada SI, Girgenrath M, Patrick Gonzalez J, Grounds MD, Nichols A, Partridge T, Passini M, Sanarica F, Schnell FJ, Wells DJ, Yokota T, Young CS, Zhong Z, Spurney C, Spencer M, De Luca A, Nagaraju K, Aartsma-Rus A.
Gordish-Dressman H, et al. Among authors: elsey d.
J Neuromuscul Dis. 2018;5(4):407-417. doi: 10.3233/JND-180324.
J Neuromuscul Dis. 2018.
PMID: 30198876
Free PMC article.
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L-cysteine stimulates hydrogen sulfide synthesis in myocardium associated with attenuation of ischemia-reperfusion injury.
Elsey DJ, Fowkes RC, Baxter GF.
Elsey DJ, et al.
J Cardiovasc Pharmacol Ther. 2010 Mar;15(1):53-9. doi: 10.1177/1074248409357743.
J Cardiovasc Pharmacol Ther. 2010.
PMID: 20133496
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Regulation of cardiovascular cell function by hydrogen sulfide (H(2)S).
Elsey DJ, Fowkes RC, Baxter GF.
Elsey DJ, et al.
Cell Biochem Funct. 2010 Mar;28(2):95-106. doi: 10.1002/cbf.1618.
Cell Biochem Funct. 2010.
PMID: 20104507
Review.
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