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MeCP2 links heterochromatin condensates and neurodevelopmental disease.
Li CH, Coffey EL, Dall'Agnese A, Hannett NM, Tang X, Henninger JE, Platt JM, Oksuz O, Zamudio AV, Afeyan LK, Schuijers J, Liu XS, Markoulaki S, Lungjangwa T, LeRoy G, Svoboda DS, Wogram E, Lee TI, Jaenisch R, Young RA. Li CH, et al. Among authors: leroy g. Nature. 2020 Oct;586(7829):440-444. doi: 10.1038/s41586-020-2574-4. Epub 2020 Jul 22. Nature. 2020. PMID: 32698189 Free PMC article.
RNA-Mediated Feedback Control of Transcriptional Condensates.
Henninger JE, Oksuz O, Shrinivas K, Sagi I, LeRoy G, Zheng MM, Andrews JO, Zamudio AV, Lazaris C, Hannett NM, Lee TI, Sharp PA, Cissé II, Chakraborty AK, Young RA. Henninger JE, et al. Among authors: leroy g. Cell. 2021 Jan 7;184(1):207-225.e24. doi: 10.1016/j.cell.2020.11.030. Epub 2020 Dec 16. Cell. 2021. PMID: 33333019 Free PMC article.
Capturing the Onset of PRC2-Mediated Repressive Domain Formation.
Oksuz O, Narendra V, Lee CH, Descostes N, LeRoy G, Raviram R, Blumenberg L, Karch K, Rocha PP, Garcia BA, Skok JA, Reinberg D. Oksuz O, et al. Among authors: leroy g. Mol Cell. 2018 Jun 21;70(6):1149-1162.e5. doi: 10.1016/j.molcel.2018.05.023. Mol Cell. 2018. PMID: 29932905 Free PMC article.
Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma.
Stafford JM, Lee CH, Voigt P, Descostes N, Saldaña-Meyer R, Yu JR, Leroy G, Oksuz O, Chapman JR, Suarez F, Modrek AS, Bayin NS, Placantonakis DG, Karajannis MA, Snuderl M, Ueberheide B, Reinberg D. Stafford JM, et al. Among authors: leroy g. Sci Adv. 2018 Oct 31;4(10):eaau5935. doi: 10.1126/sciadv.aau5935. eCollection 2018 Oct. Sci Adv. 2018. PMID: 30402543 Free PMC article.
The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.
Kapoor A, Goldberg MS, Cumberland LK, Ratnakumar K, Segura MF, Emanuel PO, Menendez S, Vardabasso C, Leroy G, Vidal CI, Polsky D, Osman I, Garcia BA, Hernando E, Bernstein E. Kapoor A, et al. Among authors: leroy g. Nature. 2010 Dec 23;468(7327):1105-9. doi: 10.1038/nature09590. Nature. 2010. PMID: 21179167 Free PMC article.
Asymmetrically modified nucleosomes.
Voigt P, LeRoy G, Drury WJ 3rd, Zee BM, Son J, Beck DB, Young NL, Garcia BA, Reinberg D. Voigt P, et al. Among authors: leroy g. Cell. 2012 Sep 28;151(1):181-93. doi: 10.1016/j.cell.2012.09.002. Cell. 2012. PMID: 23021224 Free PMC article.
Chromatin Starts to Come Clean.
Tu S, LeRoy G, Reinberg D. Tu S, et al. Among authors: leroy g. Mol Cell. 2016 Nov 3;64(3):439-441. doi: 10.1016/j.molcel.2016.10.022. Mol Cell. 2016. PMID: 27814489 Free article.
367 results