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Clinically relevant concentrations of fosfomycin combined with polymyxin B, tobramycin or ciprofloxacin enhance bacterial killing of Pseudomonas aeruginosa, but do not suppress the emergence of fosfomycin resistance.
Walsh CC, Landersdorfer CB, McIntosh MP, Peleg AY, Hirsch EB, Kirkpatrick CM, Bergen PJ. Walsh CC, et al. Among authors: hirsch eb. J Antimicrob Chemother. 2016 Aug;71(8):2218-29. doi: 10.1093/jac/dkw115. Epub 2016 Apr 26. J Antimicrob Chemother. 2016. PMID: 27118778
Ceftolozane-tazobactam and ceftazidime-avibactam activity against β-lactam-resistant Pseudomonas aeruginosa and extended-spectrum β-lactamase-producing Enterobacterales clinical isolates from U.S. medical centres.
Hirsch EB, Brigman HV, Zucchi PC, Chen A, Anderson JC, Eliopoulos GM, Cheung N, Gilbertsen A, Hunter RC, Emery CL, Bias TE. Hirsch EB, et al. J Glob Antimicrob Resist. 2020 Sep;22:689-694. doi: 10.1016/j.jgar.2020.04.017. Epub 2020 Apr 27. J Glob Antimicrob Resist. 2020. PMID: 32353524 Free article.
A Multicenter Evaluation of Ceftolozane/Tazobactam Treatment Outcomes in Immunocompromised Patients With Multidrug-Resistant Pseudomonas aeruginosa Infections.
Hart DE, Gallagher JC, Puzniak LA, Hirsch EB; C/T Alliance to deliver Real-world Evidence (CARE). Hart DE, et al. Among authors: hirsch eb. Open Forum Infect Dis. 2021 Mar 6;8(3):ofab089. doi: 10.1093/ofid/ofab089. eCollection 2021 Mar. Open Forum Infect Dis. 2021. PMID: 33796600 Free PMC article.
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