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Integrating GWAS and Transcriptomics to Identify the Molecular Underpinnings of Thermal Stress Responses in Drosophila melanogaster.
Lecheta MC, Awde DN, O'Leary TS, Unfried LN, Jacobs NA, Whitlock MH, McCabe E, Powers B, Bora K, Waters JS, Axen HJ, Frietze S, Lockwood BL, Teets NM, Cahan SH. Lecheta MC, et al. Among authors: o leary ts. Front Genet. 2020 Jun 23;11:658. doi: 10.3389/fgene.2020.00658. eCollection 2020. Front Genet. 2020. PMID: 32655626 Free PMC article.
CryoEM structure of Drosophila flight muscle thick filaments at 7 Å resolution.
Daneshparvar N, Taylor DW, O'Leary TS, Rahmani H, Abbasiyeganeh F, Previs MJ, Taylor KA. Daneshparvar N, et al. Among authors: o leary ts. Life Sci Alliance. 2020 Jul 27;3(8):e202000823. doi: 10.26508/lsa.202000823. Print 2020 Aug. Life Sci Alliance. 2020. PMID: 32718994 Free PMC article.
Skeletal MyBP-C isoforms tune the molecular contractility of divergent skeletal muscle systems.
Li A, Nelson SR, Rahmanseresht S, Braet F, Cornachione AS, Previs SB, O'Leary TS, McNamara JW, Rassier DE, Sadayappan S, Previs MJ, Warshaw DM. Li A, et al. Among authors: o leary ts. Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21882-21892. doi: 10.1073/pnas.1910549116. Epub 2019 Oct 7. Proc Natl Acad Sci U S A. 2019. PMID: 31591218 Free PMC article.
Effects of MYBPC3 loss-of-function mutations preceding hypertrophic cardiomyopathy.
Helms AS, Tang VT, O'Leary TS, Friedline S, Wauchope M, Arora A, Wasserman AH, Smith ED, Lee LM, Wen XW, Shavit JA, Liu AP, Previs MJ, Day SM. Helms AS, et al. Among authors: o leary ts. JCI Insight. 2020 Jan 30;5(2):e133782. doi: 10.1172/jci.insight.133782. JCI Insight. 2020. PMID: 31877118 Free PMC article.
Physiologic biomechanics enhance reproducible contractile development in a stem cell derived cardiac muscle platform.
Tsan YC, DePalma SJ, Zhao YT, Capilnasiu A, Wu YW, Elder B, Panse I, Ufford K, Matera DL, Friedline S, O'Leary TS, Wubshet N, Ho KKY, Previs MJ, Nordsletten D, Isom LL, Baker BM, Liu AP, Helms AS. Tsan YC, et al. Among authors: o leary ts. Nat Commun. 2021 Oct 25;12(1):6167. doi: 10.1038/s41467-021-26496-1. Nat Commun. 2021. PMID: 34697315 Free PMC article.
Defects in the Proteome and Metabolome in Human Hypertrophic Cardiomyopathy.
Previs MJ, O'Leary TS, Morley MP, Palmer BM, LeWinter M, Yob JM, Pagani FD, Petucci C, Kim MS, Margulies KB, Arany Z, Kelly DP, Day SM. Previs MJ, et al. Among authors: o leary ts. Circ Heart Fail. 2022 Jun;15(6):e009521. doi: 10.1161/CIRCHEARTFAILURE.121.009521. Epub 2022 May 11. Circ Heart Fail. 2022. PMID: 35543134 Free PMC article.
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