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A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing.
Zhang WW, Karmakar S, Gannavaram S, Dey R, Lypaczewski P, Ismail N, Siddiqui A, Simonyan V, Oliveira F, Coutinho-Abreu IV, DeSouza-Vieira T, Meneses C, Oristian J, Serafim TD, Musa A, Nakamura R, Saljoughian N, Volpedo G, Satoskar M, Satoskar S, Dagur PK, McCoy JP, Kamhawi S, Valenzuela JG, Hamano S, Satoskar AR, Matlashewski G, Nakhasi HL. Zhang WW, et al. Among authors: saljoughian n. Nat Commun. 2020 Jul 10;11(1):3461. doi: 10.1038/s41467-020-17154-z. Nat Commun. 2020. PMID: 32651371 Free PMC article.
Topical treatment with nanoliposomal Amphotericin B reduces early lesion growth but fails to induce cure in an experimental model of cutaneous leishmaniasis caused by Leishmania mexicana.
Varikuti S, Oghumu S, Saljoughian N, Pioso MS, Sedmak BE, Khamesipour A, Satoskar AR. Varikuti S, et al. Among authors: saljoughian n. Acta Trop. 2017 Sep;173:102-108. doi: 10.1016/j.actatropica.2017.06.004. Epub 2017 Jun 9. Acta Trop. 2017. PMID: 28602835 Free PMC article.
Ibrutinib treatment inhibits breast cancer progression and metastasis by inducing conversion of myeloid-derived suppressor cells to dendritic cells.
Varikuti S, Singh B, Volpedo G, Ahirwar DK, Jha BK, Saljoughian N, Viana AG, Verma C, Hamza O, Halsey G, Holcomb EA, Maryala RJ, Oghumu S, Ganju RK, Satoskar AR. Varikuti S, et al. Among authors: saljoughian n. Br J Cancer. 2020 Mar;122(7):1005-1013. doi: 10.1038/s41416-020-0743-8. Epub 2020 Feb 6. Br J Cancer. 2020. PMID: 32025027 Free PMC article.
Development of novel prime-boost strategies based on a tri-gene fusion recombinant L. tarentolae vaccine against experimental murine visceral leishmaniasis.
Saljoughian N, Taheri T, Zahedifard F, Taslimi Y, Doustdari F, Bolhassani A, Doroud D, Azizi H, Heidari K, Vasei M, Namvar Asl N, Papadopoulou B, Rafati S. Saljoughian N, et al. PLoS Negl Trop Dis. 2013 Apr 18;7(4):e2174. doi: 10.1371/journal.pntd.0002174. Print 2013. PLoS Negl Trop Dis. 2013. PMID: 23638195 Free PMC article.
CRISPR Gene Editing of Human Primary NK and T Cells for Cancer Immunotherapy.
Elmas E, Saljoughian N, de Souza Fernandes Pereira M, Tullius BP, Sorathia K, Nakkula RJ, Lee DA, Naeimi Kararoudi M. Elmas E, et al. Among authors: saljoughian n. Front Oncol. 2022 Apr 5;12:834002. doi: 10.3389/fonc.2022.834002. eCollection 2022. Front Oncol. 2022. PMID: 35449580 Free PMC article. Review.
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