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Cyclophilin inhibitors restrict Middle East respiratory syndrome coronavirus via interferon-λ in vitro and in mice.
Sauerhering L, Kupke A, Meier L, Dietzel E, Hoppe J, Gruber AD, Gattenloehner S, Witte B, Fink L, Hofmann N, Zimmermann T, Goesmann A, Nist A, Stiewe T, Becker S, Herold S, Peteranderl C. Sauerhering L, et al. Among authors: stiewe t. Eur Respir J. 2020 Nov 26;56(5):1901826. doi: 10.1183/13993003.01826-2019. Print 2020 Nov. Eur Respir J. 2020. PMID: 32616594 Free PMC article.
The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state.
Adhikary T, Wortmann A, Schumann T, Finkernagel F, Lieber S, Roth K, Toth PM, Diederich WE, Nist A, Stiewe T, Kleinesudeik L, Reinartz S, Müller-Brüsselbach S, Müller R. Adhikary T, et al. Among authors: stiewe t. Nucleic Acids Res. 2015 May 26;43(10):5033-51. doi: 10.1093/nar/gkv331. Epub 2015 Apr 30. Nucleic Acids Res. 2015. PMID: 25934804 Free PMC article.
Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment.
Schumann T, Adhikary T, Wortmann A, Finkernagel F, Lieber S, Schnitzer E, Legrand N, Schober Y, Nockher WA, Toth PM, Diederich WE, Nist A, Stiewe T, Wagner U, Reinartz S, Müller-Brüsselbach S, Müller R. Schumann T, et al. Among authors: stiewe t. Oncotarget. 2015 May 30;6(15):13416-33. doi: 10.18632/oncotarget.3826. Oncotarget. 2015. PMID: 25968567 Free PMC article.
Immune and Inflammatory Cell Composition of Human Lung Cancer Stroma.
Banat GA, Tretyn A, Pullamsetti SS, Wilhelm J, Weigert A, Olesch C, Ebel K, Stiewe T, Grimminger F, Seeger W, Fink L, Savai R. Banat GA, et al. Among authors: stiewe t. PLoS One. 2015 Sep 28;10(9):e0139073. doi: 10.1371/journal.pone.0139073. eCollection 2015. PLoS One. 2015. PMID: 26413839 Free PMC article.
CRISPR-Cas9-based target validation for p53-reactivating model compounds.
Wanzel M, Vischedyk JB, Gittler MP, Gremke N, Seiz JR, Hefter M, Noack M, Savai R, Mernberger M, Charles JP, Schneikert J, Bretz AC, Nist A, Stiewe T. Wanzel M, et al. Among authors: stiewe t. Nat Chem Biol. 2016 Jan;12(1):22-8. doi: 10.1038/nchembio.1965. Epub 2015 Nov 23. Nat Chem Biol. 2016. PMID: 26595461 Free PMC article.
150 results