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Cyclophilin inhibitors restrict Middle East respiratory syndrome coronavirus via interferon-λ in vitro and in mice.
Sauerhering L, Kupke A, Meier L, Dietzel E, Hoppe J, Gruber AD, Gattenloehner S, Witte B, Fink L, Hofmann N, Zimmermann T, Goesmann A, Nist A, Stiewe T, Becker S, Herold S, Peteranderl C. Sauerhering L, et al. Among authors: gruber ad. Eur Respir J. 2020 Nov 26;56(5):1901826. doi: 10.1183/13993003.01826-2019. Print 2020 Nov. Eur Respir J. 2020. PMID: 32616594 Free PMC article.
Streptococcus pneumoniae-induced regulation of cyclooxygenase-2 in human lung tissue.
Szymanski KV, Toennies M, Becher A, Fatykhova D, N'Guessan PD, Gutbier B, Klauschen F, Neuschaefer-Rube F, Schneider P, Rueckert J, Neudecker J, Bauer TT, Dalhoff K, Drömann D, Gruber AD, Kershaw O, Temmesfeld-Wollbrueck B, Suttorp N, Hippenstiel S, Hocke AC. Szymanski KV, et al. Among authors: gruber ad. Eur Respir J. 2012 Dec;40(6):1458-67. doi: 10.1183/09031936.00186911. Epub 2012 Mar 22. Eur Respir J. 2012. PMID: 22441740 Free article.
Macrophage-expressed IFN-β contributes to apoptotic alveolar epithelial cell injury in severe influenza virus pneumonia.
Högner K, Wolff T, Pleschka S, Plog S, Gruber AD, Kalinke U, Walmrath HD, Bodner J, Gattenlöhner S, Lewe-Schlosser P, Matrosovich M, Seeger W, Lohmeyer J, Herold S. Högner K, et al. Among authors: gruber ad. PLoS Pathog. 2013 Feb;9(2):e1003188. doi: 10.1371/journal.ppat.1003188. Epub 2013 Feb 28. PLoS Pathog. 2013. PMID: 23468627 Free PMC article.
Emerging human middle East respiratory syndrome coronavirus causes widespread infection and alveolar damage in human lungs.
Hocke AC, Becher A, Knepper J, Peter A, Holland G, Tönnies M, Bauer TT, Schneider P, Neudecker J, Muth D, Wendtner CM, Rückert JC, Drosten C, Gruber AD, Laue M, Suttorp N, Hippenstiel S, Wolff T. Hocke AC, et al. Among authors: gruber ad. Am J Respir Crit Care Med. 2013 Oct 1;188(7):882-6. doi: 10.1164/rccm.201305-0954LE. Am J Respir Crit Care Med. 2013. PMID: 24083868 No abstract available.
IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid.
Naujoks J, Tabeling C, Dill BD, Hoffmann C, Brown AS, Kunze M, Kempa S, Peter A, Mollenkopf HJ, Dorhoi A, Kershaw O, Gruber AD, Sander LE, Witzenrath M, Herold S, Nerlich A, Hocke AC, van Driel I, Suttorp N, Bedoui S, Hilbi H, Trost M, Opitz B. Naujoks J, et al. Among authors: gruber ad. PLoS Pathog. 2016 Feb 1;12(2):e1005408. doi: 10.1371/journal.ppat.1005408. eCollection 2016 Feb. PLoS Pathog. 2016. PMID: 26829557 Free PMC article.
Tyk2 as a target for immune regulation in human viral/bacterial pneumonia.
Berg J, Zscheppang K, Fatykhova D, Tönnies M, Bauer TT, Schneider P, Neudecker J, Rückert JC, Eggeling S, Schimek M, Gruber AD, Suttorp N, Hippenstiel S, Hocke AC. Berg J, et al. Among authors: gruber ad. Eur Respir J. 2017 Jul 13;50(1):1601953. doi: 10.1183/13993003.01953-2016. Print 2017 Jul. Eur Respir J. 2017. PMID: 28705941 Free article.
Spectrum of pathogen- and model-specific histopathologies in mouse models of acute pneumonia.
Dietert K, Gutbier B, Wienhold SM, Reppe K, Jiang X, Yao L, Chaput C, Naujoks J, Brack M, Kupke A, Peteranderl C, Becker S, von Lachner C, Baal N, Slevogt H, Hocke AC, Witzenrath M, Opitz B, Herold S, Hackstein H, Sander LE, Suttorp N, Gruber AD. Dietert K, et al. Among authors: gruber ad. PLoS One. 2017 Nov 20;12(11):e0188251. doi: 10.1371/journal.pone.0188251. eCollection 2017. PLoS One. 2017. PMID: 29155867 Free PMC article.
Digital Image Analyses on Whole-Lung Slides in Mouse Models of Acute Pneumonia.
Dietert K, Nouailles G, Gutbier B, Reppe K, Berger S, Jiang X, Schauer AE, Hocke AC, Herold S, Slevogt H, Witzenrath M, Suttorp N, Gruber AD. Dietert K, et al. Among authors: gruber ad. Am J Respir Cell Mol Biol. 2018 Apr;58(4):440-448. doi: 10.1165/rcmb.2017-0337MA. Am J Respir Cell Mol Biol. 2018. PMID: 29361238
318 results