Nagashima H - Search Results

1

Poly(ADP-ribose) Glycohydrolase Inhibition Sequesters NAD⁺ to Potentiate the Metabolic Lethality of Alkylating Chemotherapy in IDH-Mutant Tumor Cells.

Nagashima H, Lee CK, Tateishi K, Higuchi F, Subramanian M, Rafferty S, Melamed L, Miller JJ, Wakimoto H, Cahill DP. Nagashima H, et al. Cancer Discov. 2020 Nov;10(11):1672-1689. doi: 10.1158/2159-8290.CD-20-0226. Epub 2020 Jun 30. Cancer Discov. 2020. PMID: 32606138 Free PMC article.

2

Restoration of Temozolomide Sensitivity by PARP Inhibitors in Mismatch Repair Deficient Glioblastoma is Independent of Base Excision Repair.

Higuchi F, Nagashima H, Ning J, Koerner MVA, Wakimoto H, Cahill DP. Higuchi F, et al. Among authors: nagashima h. Clin Cancer Res. 2020 Apr 1;26(7):1690-1699. doi: 10.1158/1078-0432.CCR-19-2000. Epub 2020 Jan 3. Clin Cancer Res. 2020. PMID: 31900275 Free PMC article.

3

Sirtuin activation targets IDH-mutant tumors.

Miller JJ, Fink A, Banagis JA, Nagashima H, Subramanian M, Lee CK, Melamed L, Tummala SS, Tateishi K, Wakimoto H, Cahill DP. Miller JJ, et al. Among authors: nagashima h. Neuro Oncol. 2021 Jan 30;23(1):53-62. doi: 10.1093/neuonc/noaa180. Neuro Oncol. 2021. PMID: 32710757 Free PMC article.

4

IDH-mutant gliomas harbor fewer regulatory T cells in humans and mice.

Richardson LG, Nieman LT, Stemmer-Rachamimov AO, Zheng XS, Stafford K, Nagashima H, Miller JJ, Kiyokawa J, Ting DT, Wakimoto H, Cahill DP, Choi BD, Curry WT. Richardson LG, et al. Among authors: nagashima h. Oncoimmunology. 2020 Aug 20;9(1):1806662. doi: 10.1080/2162402X.2020.1806662. Oncoimmunology. 2020. PMID: 32923170 Free PMC article.

5

Local Targeting of NAD⁺ Salvage Pathway Alters the Immune Tumor Microenvironment and Enhances Checkpoint Immunotherapy in Glioblastoma.

Li M, Kirtane AR, Kiyokawa J, Nagashima H, Lopes A, Tirmizi ZA, Lee CK, Traverso G, Cahill DP, Wakimoto H. Li M, et al. Among authors: nagashima h. Cancer Res. 2020 Nov 15;80(22):5024-5034. doi: 10.1158/0008-5472.CAN-20-1094. Epub 2020 Sep 30. Cancer Res. 2020. PMID: 32998997 Free PMC article.

6

Local Targeting of NAD⁺ Salvage Pathway Alters the Immune Tumor Microenvironment and Enhances Checkpoint Immunotherapy in Glioblastoma.

Li M, Kirtane AR, Kiyokawa J, Nagashima H, Lopes A, Tirmizi ZA, Lee CK, Traverso G, Cahill DP, Wakimoto H. Li M, et al. Among authors: nagashima h. Cancer Res. 2021 Apr 1;81(7):1922. doi: 10.1158/0008-5472.CAN-21-0525. Cancer Res. 2021. PMID: 34003791 No abstract available.

7

CDKN2A/B homozygous deletion sensitizes IDH-mutant glioma to CDK4/6 inhibition.

Nasser AM, Melamed L, Wetzel E, Chang CC, Nagashima H, Kitagawa Y, Muzyka L, Wakimoto H, Cahill DP, Miller JJ. Nasser AM, et al. Among authors: nagashima h. Clin Cancer Res. 2024 May 8. doi: 10.1158/1078-0432.CCR-24-0562. Online ahead of print. Clin Cancer Res. 2024. PMID: 38718141

8

Ror1 is expressed inducibly by Notch and hypoxia signaling and regulates stem cell-like property of glioblastoma cells.

Ishikawa T, Ogura Y, Tanaka K, Nagashima H, Sasayama T, Endo M, Minami Y. Ishikawa T, et al. Among authors: nagashima h. Cancer Sci. 2023 Feb;114(2):561-573. doi: 10.1111/cas.15630. Epub 2022 Nov 25. Cancer Sci. 2023. PMID: 36314076 Free PMC article.

9

Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma.

Nagashima H, Tanaka K, Sasayama T, Irino Y, Sato N, Takeuchi Y, Kyotani K, Mukasa A, Mizukawa K, Sakata J, Yamamoto Y, Hosoda K, Itoh T, Sasaki R, Kohmura E. Nagashima H, et al. Neuro Oncol. 2016 Nov;18(11):1559-1568. doi: 10.1093/neuonc/now090. Epub 2016 May 5. Neuro Oncol. 2016. PMID: 27154922 Free PMC article.

10

[Clinical Features and Treatment Strategy of Vertebral Artery Injury Associated with Cervical Spine Trauma].

Fujita Y, Aihara H, Nagashima H, Morishita A, Aoki K, Takayama H, Harada T, Tohma Y, Hara Y, Kohmura E. Fujita Y, et al. Among authors: nagashima h. No Shinkei Geka. 2018 Aug;46(8):663-671. doi: 10.11477/mf.1436203791. No Shinkei Geka. 2018. PMID: 30135288 Japanese.

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