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Targeting Pathological Tau by Small Molecule Inhibition of the Poly(A):MSUT2 RNA-Protein Interaction.
ACS Chem Neurosci. 2020 Aug 5;11(15):2277-2285. doi: 10.1021/acschemneuro.0c00214. Epub 2020 Jul 9.
ACS Chem Neurosci. 2020.
PMID: 32589834
Free PMC article.
AlphaScreen Identifies MSUT2 Inhibitors for Tauopathy-Targeting Therapeutic Discovery.
Baker JD, Uhrich RL, Strovas TJ, Saxton AD, Kraemer BC.
Baker JD, et al. Among authors: uhrich rl.
SLAS Discov. 2021 Mar;26(3):400-409. doi: 10.1177/2472555220958387. Epub 2020 Sep 28.
SLAS Discov. 2021.
PMID: 32981422
Free PMC article.
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A drug repurposing screen identifies hepatitis C antivirals as inhibitors of the SARS-CoV2 main protease.
Baker JD, Uhrich RL, Kraemer GC, Love JE, Kraemer BC.
Baker JD, et al. Among authors: uhrich rl.
PLoS One. 2021 Feb 1;16(2):e0245962. doi: 10.1371/journal.pone.0245962. eCollection 2021.
PLoS One. 2021.
PMID: 33524017
Free PMC article.
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Tau-RNA complexes inhibit microtubule polymerization and drive disease-relevant conformation change.
McMillan PJ, Benbow SJ, Uhrich R, Saxton A, Baum M, Strovas T, Wheeler JM, Baker J, Liachko NF, Keene CD, Latimer CS, Kraemer BC.
McMillan PJ, et al.
Brain. 2023 Aug 1;146(8):3206-3220. doi: 10.1093/brain/awad032.
Brain. 2023.
PMID: 36732296
Free PMC article.
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