Keshari KR - Search Results

1

Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition.

Ngo B, Kim E, Osorio-Vasquez V, Doll S, Bustraan S, Liang RJ, Luengo A, Davidson SM, Ali A, Ferraro GB, Fischer GM, Eskandari R, Kang DS, Ni J, Plasger A, Rajasekhar VK, Kastenhuber ER, Bacha S, Sriram RK, Stein BD, Bakhoum SF, Snuderl M, Cotzia P, Healey JH, Mainolfi N, Suri V, Friedman A, Manfredi M, Sabatini DM, Jones DR, Yu M, Zhao JJ, Jain RK, Keshari KR, Davies MA, Vander Heiden MG, Hernando E, Mann M, Cantley LC, Pacold ME. Ngo B, et al. Among authors: keshari kr. Cancer Discov. 2020 Sep;10(9):1352-1373. doi: 10.1158/2159-8290.CD-19-1228. Epub 2020 Jun 22. Cancer Discov. 2020. PMID: 32571778 Free PMC article.

2

Sampling Hyperpolarized Molecules Utilizing a 1 Tesla Permanent Magnetic Field.

Tee SS, DiGialleonardo V, Eskandari R, Jeong S, Granlund KL, Miloushev V, Poot AJ, Truong S, Alvarez JA, Aldeborgh HN, Keshari KR. Tee SS, et al. Among authors: keshari kr. Sci Rep. 2016 Sep 6;6:32846. doi: 10.1038/srep32846. Sci Rep. 2016. PMID: 27597137 Free PMC article.

3

Multinuclear NMR and MRI Reveal an Early Metabolic Response to mTOR Inhibition in Sarcoma.

Di Gialleonardo V, Aldeborgh HN, Miloushev V, Folkers KM, Granlund K, Tap WD, Lewis JS, Weber WA, Keshari KR. Di Gialleonardo V, et al. Among authors: keshari kr. Cancer Res. 2017 Jun 1;77(11):3113-3120. doi: 10.1158/0008-5472.CAN-16-3310. Epub 2017 Apr 6. Cancer Res. 2017. PMID: 28386017 Free PMC article.

4

Real-time quantitative analysis of metabolic flux in live cells using a hyperpolarized micromagnetic resonance spectrometer.

Jeong S, Eskandari R, Park SM, Alvarez J, Tee SS, Weissleder R, Kharas MG, Lee H, Keshari KR. Jeong S, et al. Among authors: keshari kr. Sci Adv. 2017 Jun 16;3(6):e1700341. doi: 10.1126/sciadv.1700341. eCollection 2017 Jun. Sci Adv. 2017. PMID: 28630930 Free PMC article.

5

Targeted AKT Inhibition in Prostate Cancer Cells and Spheroids Reduces Aerobic Glycolysis and Generation of Hyperpolarized [1-¹³C] Lactate.

Tee SS, Suster I, Truong S, Jeong S, Eskandari R, DiGialleonardo V, Alvarez JA, Aldeborgh HN, Keshari KR. Tee SS, et al. Among authors: keshari kr. Mol Cancer Res. 2018 Mar;16(3):453-460. doi: 10.1158/1541-7786.MCR-17-0458. Epub 2018 Jan 12. Mol Cancer Res. 2018. PMID: 29330287 Free PMC article.

6

A non-synthetic approach to extending the lifetime of hyperpolarized molecules using D₂O solvation.

Cho A, Eskandari R, Miloushev VZ, Keshari KR. Cho A, et al. Among authors: keshari kr. J Magn Reson. 2018 Oct;295:57-62. doi: 10.1016/j.jmr.2018.08.001. Epub 2018 Aug 2. J Magn Reson. 2018. PMID: 30099234 Free PMC article.

7

Hyperpolarized MRI Visualizes Warburg Effects and Predicts Treatment Response to mTOR Inhibitors in Patient-Derived ccRCC Xenograft Models.

Dong Y, Eskandari R, Ray C, Granlund KL, Santos-Cunha LD, Miloushev VZ, Tee SS, Jeong S, Aras O, Chen YB, Cheng EH, Hsieh JJ, Keshari KR. Dong Y, et al. Among authors: keshari kr. Cancer Res. 2019 Jan 1;79(1):242-250. doi: 10.1158/0008-5472.CAN-18-2231. Epub 2018 Nov 20. Cancer Res. 2019. PMID: 30459151 Free PMC article.

8

Hyperpolarized [6-¹³C,¹⁵N₃]-Arginine as a Probe for in Vivo Arginase Activity.

Cho A, Eskandari R, Granlund KL, Keshari KR. Cho A, et al. Among authors: keshari kr. ACS Chem Biol. 2019 Apr 19;14(4):665-673. doi: 10.1021/acschembio.8b01044. Epub 2019 Mar 27. ACS Chem Biol. 2019. PMID: 30893552 Free PMC article.

9

Dynamic volumetric hyperpolarized ¹³ C imaging with multi-echo EPI.

Deh K, Granlund KL, Eskandari R, Kim N, Mamakhanyan A, Keshari KR. Deh K, et al. Among authors: keshari kr. Magn Reson Med. 2021 Feb;85(2):978-986. doi: 10.1002/mrm.28466. Epub 2020 Aug 15. Magn Reson Med. 2021. PMID: 32820566 Free PMC article.

10

Multi-sample measurement of hyperpolarized pyruvate-to-lactate flux in melanoma cells.

Lees H, Millan M, Ahamed F, Eskandari R, Granlund KL, Jeong S, Keshari KR. Lees H, et al. Among authors: keshari kr. NMR Biomed. 2021 Mar;34(3):e4447. doi: 10.1002/nbm.4447. Epub 2020 Dec 12. NMR Biomed. 2021. PMID: 33314422 Free PMC article.

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