Dawson JE - Search Results

1

Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition.

Dawson JE, Bah A, Zhang Z, Vernon RM, Lin H, Chong PA, Vanama M, Sonenberg N, Gradinaru CC, Forman-Kay JD. Dawson JE, et al. Nat Commun. 2020 Jun 19;11(1):3146. doi: 10.1038/s41467-020-16783-8. Nat Commun. 2020. PMID: 32561718 Free PMC article.

2

Multisite phosphorylation and binding alter conformational dynamics of the 4E-BP2 protein.

Smyth S, Zhang Z, Bah A, Tsangaris TE, Dawson J, Forman-Kay JD, Gradinaru CC. Smyth S, et al. Biophys J. 2022 Aug 16;121(16):3049-3060. doi: 10.1016/j.bpj.2022.07.015. Epub 2022 Jul 15. Biophys J. 2022. PMID: 35841142 Free PMC article.

3

Direct Binding of the Corrector VX-809 to Human CFTR NBD1: Evidence of an Allosteric Coupling between the Binding Site and the NBD1:CL4 Interface.

Hudson RP, Dawson JE, Chong PA, Yang Z, Millen L, Thomas PJ, Brouillette CG, Forman-Kay JD. Hudson RP, et al. Among authors: dawson je. Mol Pharmacol. 2017 Aug;92(2):124-135. doi: 10.1124/mol.117.108373. Epub 2017 May 25. Mol Pharmacol. 2017. PMID: 28546419

4

Stabilization of a nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator yields insight into disease-causing mutations.

Vernon RM, Chong PA, Lin H, Yang Z, Zhou Q, Aleksandrov AA, Dawson JE, Riordan JR, Brouillette CG, Thibodeau PH, Forman-Kay JD. Vernon RM, et al. Among authors: dawson je. J Biol Chem. 2017 Aug 25;292(34):14147-14164. doi: 10.1074/jbc.M116.772335. Epub 2017 Jun 27. J Biol Chem. 2017. PMID: 28655774 Free PMC article.

5

Allosteric coupling between the intracellular coupling helix 4 and regulatory sites of the first nucleotide-binding domain of CFTR.

Dawson JE, Farber PJ, Forman-Kay JD. Dawson JE, et al. PLoS One. 2013 Sep 18;8(9):e74347. doi: 10.1371/journal.pone.0074347. eCollection 2013. PLoS One. 2013. PMID: 24058550 Free PMC article.

6

Molecular structural analysis of a novel and de-novo mutation in the SERPINC1 gene associated with type 1 antithrombin deficiency.

Wang TF, Dawson JE, Forman-Kay JD, Kahr WHA, Williams S, Chan AK, Kumar R. Wang TF, et al. Among authors: dawson je. Br J Haematol. 2017 May;177(4):654-656. doi: 10.1111/bjh.14090. Epub 2016 Apr 21. Br J Haematol. 2017. PMID: 27098850 Free article. No abstract available.

7

c.1058C>T variant in the SERPINC1 gene is pathogenic for antithrombin deficiency.

Kumar R, Dawson JE, Chan AK, Forman-Kay JD, Kahr WH, Williams S. Kumar R, et al. Among authors: dawson je. Br J Haematol. 2015 Jul;170(1):123-5. doi: 10.1111/bjh.13261. Epub 2014 Dec 19. Br J Haematol. 2015. PMID: 25522812 Free article. No abstract available.

8

Clinical presentation and molecular basis of congenital antithrombin deficiency in children: a cohort study.

Kumar R, Chan AK, Dawson JE, Forman-Kay JD, Kahr WH, Williams S. Kumar R, et al. Among authors: dawson je. Br J Haematol. 2014 Jul;166(1):130-9. doi: 10.1111/bjh.12842. Epub 2014 Mar 29. Br J Haematol. 2014. PMID: 24684277 Free article.

9

Structural and Dynamic Effects of PTEN C-Terminal Tail Phosphorylation.

Smith IN, Dawson JE, Krieger J, Thacker S, Bahar I, Eng C. Smith IN, et al. Among authors: dawson je. J Chem Inf Model. 2022 Sep 12;62(17):4175-4190. doi: 10.1021/acs.jcim.2c00441. Epub 2022 Aug 24. J Chem Inf Model. 2022. PMID: 36001481 Free PMC article.

10

Partnering With Patients, Caregivers, and Clinicians to Determine Research Priorities for Concussion.

Osmond MH, Legace E, Gill PJ, Correll R, Cowan K, Dawson JE, Duncan R, Fox E, Gupta K, Kolstad AT, Langevin LM, Macarthur C, Macklem R, Olszewska K, Reed N, Zemek R; Canadian Traumatic Brain Injury Research Consortium. Osmond MH, et al. Among authors: dawson je. JAMA Netw Open. 2023 Jun 1;6(6):e2316383. doi: 10.1001/jamanetworkopen.2023.16383. JAMA Netw Open. 2023. PMID: 37285158 Free PMC article.

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